ArticleNeurogastroenterology and motility2020
Improving the utility of high-resolution manometry for the diagnosis of defecatory disorders in women with chronic constipation.
Article in Neurogastroenterology and motility, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Anorectal manometry to diagnose dyssynergic defecation: Systematic review and meta-analysis of diagnostic test accuracy.Neurogastroenterology and motility · 2021Pooled it
- A randomized double-blind trial of clonidine and colesevelam for women with fecal incontinence.Neurogastroenterology and motility · 2024Trial
- Fecobionics assessment of the effect of position on defecatory efficacy in normal subjects.Techniques in coloproctology · 2021Trial
- High-resolution anorectal manometry in chronic constipation-Defining dysfunction beyond diagnosis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- Inadequate Propulsion and Pelvic Floor Relaxation in Dyssynergic Defecation: Insights From Synchronous Proctomanometry.Gastroenterology · 2025Article
- High-Resolution Anorectal Manometry and Balloon Expulsion Test Outcomes in Functional Constipation: A Comparative Study.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Defecatory disorders are a common cause of chronic constipation in Parkinson disease.Neurogastroenterology and motility · 2024Article
- Optimizing the Utility of Anorectal Manometry for Diagnosis and Therapy: A Roundtable Review and Recommendations.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023Review
- Comparison of Anorectal Manometry, Rectal Balloon Expulsion Test, and Defecography for Diagnosing Defecatory Disorders.Gastroenterology · 2022Article
- Reproducibility of high-resolution manometry among healthy and constipated persons.Neurogastroenterology and motility · 2022Article
- Automated extraction of anorectal pressures from high-resolution manometry reports.Neurogastroenterology and motility · 2022Article
- Optimizing techniques for measuring anal resting and squeeze pressures with high-resolution manometry.Neurogastroenterology and motility · 2022Article
- Abdomino-anal Dyscoordination in Defecatory Disorders.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022Article
- Review of the indications, methods, and clinical utility of anorectal manometry and the rectal balloon expulsion test.Neurogastroenterology and motility · 2022Review
- Inadequate Rectal Pressure and Insufficient Relaxation and Abdominopelvic Coordination in Defecatory Disorders.Gastroenterology · 2022Article
- Diagnostic Strategy and Tools for Identifying Defecatory Disorders.Gastroenterology clinics of North America · 2022Review
- A comparison of rectoanal pressures during Valsalva maneuver and evacuation uncovers rectoanal discoordination in defecatory disorders.Neurogastroenterology and motility · 2021Article
- A new method for assessing anal distensibility with a barostat and magnetic resonance imaging in healthy and constipated women.Neurogastroenterology and motility · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundWe compared the utility of existing and modified versions of high-resolution manometry for diagnosing defecatory disorders (DD).
methodsIn 64 healthy and 136 constipated women, we compared left lateral (LL) and seated manometry, and analyzed with existing (ManoView™) and new methods, for discriminating between constipated patients with normal and prolonged rectal balloon expulsion time (BET). In both positions, the rectoanal gradient (RAG) and, for the new analysis, the pressure topography pattern during evacuation were used to discriminate between constipated patients without and with DD. KEY
resultsThe BET was prolonged, suggestive of a DD, in 52 patients (38%). During evacuation, rectoanal pressures and the RAG were greater in the seated than the LL position (P≤.001). The new analysis identified 4 rectoanal pressure patterns. In the seated position, the BET was associated with the pattern (P=.0001), being prolonged in, respectively, 45%, 15%, 53%, and 0% of patients with minimal change, anal relaxation, paradoxical contraction, and transmission. Within each pattern, the RAG was greater (ie, less negative, P<.0001) in patients with a normal than a prolonged BET. Compared to the ManoView™ RAG in the LL position, the integrated analysis (ie, pattern and new RAG) in the LL position (P<.01) and the seated ManoView™ gradient (P=.02) were more effective for discriminating between constipated patients without and with DD. CONCLUSIONS & INFERENCES: Anorectal HRM ideally should be performed in the more physiological seated position and analyzed by a two-tier approach, which incorporates the overall pattern followed by the rectoanal gradient. These findings reinforce the utility of manometry for diagnosing DD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.