ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2021
Quality of life and mortality after surgical treatment for vertebral osteomyelitis (VO): a prospective study.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 53 citations in OpenAlex.
- Nomogram for predicting inadequate treatment response in vertebral osteomyelitis.Annals of medicine · 2026Article
- A Novel Gelatin Hydrogel-Based Drug-Delivery System Promotes Antimicrobial Efficacy in a Pyogenic Spondylodiscitis Rat Model.JOR spine · 2026Article
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- Clinical Manifestations, Long-Term Trends, and Risk Factors for Treatment Failure in Native Vertebral Osteomyelitis: A 26-Year Mayo Clinic Experience.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Article
- Impact of Culture Status on Outcomes in Vertebral Osteomyelitis: A Retrospective Cohort Study of 206 Patients.Global spine journal · 2026Article
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- Evaluation of Intravenous Administration of Anti-Infective Agents and Documentation Quality in Orthopedics and Trauma Surgery: A Quantitative Study on Discrepancies Between Physician Prescriptions and Nursing Records.Antibiotics (Basel, Switzerland) · 2026Article
- Prediction and risk factors for one year mortality in patients after surgery for pyogenic spondylodiscitis.Neurosurgical review · 2026Article
- Is Conservative Treatment Superior to Surgical Intervention in Hematogenous Primary Septic Spinal Infection in Terms of Mortality, Recurrence, and Hospital Stay? A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Early and late mortality in vertebral osteomyelitis: who dies within the first year after diagnosis.Infection · 2025Article
- Vertebral osteomyelitis in patients with an underlying malignancy or chronic kidney disease - who is at higher risk for adverse outcome?Infection · 2025Article
- Pain and Disability Reduction Following Rib Manipulation in a Patient Recovering from Osteomyelitis of the Thoracic Spine.Healthcare (Basel, Switzerland) · 2025Article
- Development and validation of a prognostic nomogram model for severe osteomyelitis patients.Scientific reports · 2025Article
- Diagnosis and management of de novo non-specific spinal infections: European Association of Neurosurgical Societies (EANS) Spine Section Delphi consensus recommendations.Brain & spine · 2025Article
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- Factors prolonging antibiotic duration and impact of early surgery in thoracolumbar pyogenic spondylitis treated with minimally invasive posterior fixation.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- A post-hoc analysis of risk factors for poor quality of life after surgical treatment of spondylodiscitis.Scientific reports · 2024Article
- Biofilm Formation, Antibiotic Resistance, and Infection (BARI): The Triangle of Death.Journal of clinical medicine · 2024Review
- [Antibiotics (Basel, Switzerland) · 2024Article
- Article
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeVertebral osteomyelitis (VO) has a high mortality and leads to chronic pain and functional disability. Surgical treatment is often necessary. To date, little is known about the consequences of surgery on patient outcome. The aim of this study was to determine the quality of life (QoL) and mortality rates of surgically treated VO patients for a period of 2 years.
methodsPatients with VO undergoing surgical treatment in a tertiary referral hospital from 2008 to 2015 were included prospectively. Data were collected before (T0) as well as 1 year (T1) and 2 years (T2) post-surgery. Within the European Spine Tango registry, prospective patient and QoL data were collected using validated outcome scores: Oswestry Disability Index, Short Form 36/EuroQol, Visual Analog Scale, and Core Outcome Measures Index.
resultsFrom 195 patients surgically treated for VO, QoL data were available from 136 patients at T0, 100 patients at T1, and 82 patients at T2, respectively. The 1- and 2-year mortality rates were 20% and 23%. Mainly all QoL outcome scores showed significant improvement at T1 and did not change significantly from T1 to T2.
conclusionSurgical treatment of VO patients leads to significantly improved QoL. Nevertheless, QoL levels were below those of the general population. Our results underscore that spine disability questionnaires measuring QoL are mandatory to demonstrate comprehensively the severity of this entity. Our study confirms a high mortality and points out the role of VO as a potentially life-threatening condition.
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