ArticleEsophagus : official journal of the Japan Esophageal Society2021
Efficacy of enhanced prehabilitation for patients with esophageal cancer undergoing esophagectomy.
Article in Esophagus : official journal of the Japan Esophageal Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 5 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 5 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Effects of different rehabilitation strategies on physical function and complications in postoperative patients with esophageal cancer: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Effect of prehabilitation on postoperative outcomes in patients with upper gastrointestinal tract cancer: meta-analysis.BJS open · 2025Pooled it
- Pooled it
- Effects of unimodal or multimodal prehabilitation on patients undergoing surgery for esophagogastric cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Pooled it
- Physiotherapy Regimens in Esophagectomy and Gastrectomy: a Systematic Review and Meta-Analysis.Annals of surgical oncology · 2022Pooled it
- Review
- Comparison of utilization trends, outcomes, and costs between open and minimally invasive esophagectomy.Surgical endoscopy · 2025Article
- Physical fitness predicts post-esophagectomy complications after chemoradiotherapy: a pilot study.BMC sports science, medicine & rehabilitation · 2025Article
- Measurement and optimization of perioperative risk among patients undergoing surgery for esophageal cancer.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024Article
- Effect of Three Weeks of High-Intensity, Long-Term Preoperative Rehabilitation for Esophageal Cancer Patients with Stroke Sequelae Who Were Considered Unfit for Surgery Due to Low Activity: A Case Report.Healthcare (Basel, Switzerland) · 2023Article
- Article
- Perspectives on the Direction of Cancer Prehabilitation in the Pandemic and Beyond.Archives of rehabilitation research and clinical translation · 2022Article
- Impact of preoperative skeletal muscle mass and physical performance on short-term and long-term postoperative outcomes in patients with esophageal cancer after esophagectomy.Annals of gastroenterological surgery · 2022Article
- Trajectories of Health-Related Quality of Life, Health Literacy, and Self-Efficacy in Curatively-Treated Patients with Esophageal Cancer: A Longitudinal Single-Center Study in Italy.Journal of patient experience · 2021Article
- Human Microbiota in Esophageal Adenocarcinoma: Pathogenesis, Diagnosis, Prognosis and Therapeutic Implications.Frontiers in microbiology · 2021Review
- Multiphasic Prehabilitation Across the Cancer Continuum: A Narrative Review and Conceptual Framework.Frontiers in oncology · 2020Review
- Does VOIn vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
16 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral studies have demonstrated that prehabilitation helps reduce the incidence of postoperative complications. In this study, we investigated the safety and efficacy of enhanced prehabilitation (EP) in the hospital for patients with esophageal cancer.
methodsWe retrospectively reviewed the data of 48 consecutive patients who underwent radical esophagectomy with gastric tube reconstruction between September 2015 and June 2019. EP program had been introduced in August 2017. In the EP group, patients received the EP program during hospitalization 7 days before surgery in addition to conventional perioperative rehabilitation. The EP program consisted of aerobic exercise and muscle strength training in the morning and afternoon. Operative outcomes were compared between patients who received EP (EP group; 23 patients) and patients who did not receive EP (control group; 25 patients).
resultsThe preoperative (EP group vs. control group, 492.9 ± 79.7 vs. 418.9 ± 71.8 m, p < 0.001) and postoperative (EP group vs. control group, 431.5 ± 80 vs. 378 ± 68.7 m, p < 0.001) 6-min walk distance was significantly higher in the EP group than in the control group. The respiratory complications rate was significantly lower in the EP group (4.3%) than in the control group (36%) (p = 0.007). The incidence of atelectasis was particularly significantly lower in the EP group (0%) than in the control group (24%) (p = 0.012).
conclusionsEP was performed safely for patients before esophagectomy. EP improved the exercise tolerance of the patients before esophagectomy and might be useful in preventing respiratory complications.
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