Evidence map›Paper›PMID 32613303›Full record

ArticleSurgical endoscopy2021

The effect of non-curative endoscopic resection on cT1N0M0 colorectal carcinoma patients who underwent additional surgery.

Yu Liu, Ran Li, Wenju Chang, Li Ren, Ye Wei, Tianyu Liu, Yijiao Chen, Minzhi Lv, Yunshi Zhong, Jianmin Xu

Abstract read
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In one paragraph

Article in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yu Liu *Colorectal Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China.
Ran Li *Endoscopic Center, Zhongshan Hospital, Fudan University, Shanghai, China.
Wenju Chang *Colorectal Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China.
Li Ren *Colorectal Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China.
Ye WeiColorectal Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China.
Tianyu LiuColorectal Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China.
Yijiao ChenColorectal Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China.
Minzhi LvDepartment of Biostatistics, Zhongshan Hospital, Fudan University, Shanghai, China.
Yunshi ZhongColorectal Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China. 13564623481@126.com.
Jianmin XuColorectal Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, China. xujmin@aliyun.com.ORCID http://orcid.org/0000-0001-5441-8240
Sun Yat-sen University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimRadical surgery is recommended for T1 colorectal cancer with non-curative endoscopic resection. However, there is still insufficient evidence about whether the non-curative endoscopic resection prior to surgical resection affects the short-term and long-term outcomes of patients. The purpose of this study was to investigate the effect of non-curative endoscopic resection before surgical resection on short-term and long-term outcomes in patients with T1 colorectal cancer. PATIENTS AND

methodsPatients with clinical T1N0M0 (cT1N0M0) colorectal cancer who underwent direct surgery or additional radical surgery after non-curative endoscopic resection were collected. We evaluated postoperative complications and long-term prognosis between the two groups.

resultsFrom 2011 to 2017, 779 patients were clinically diagnosed with T1N0M0 colorectal cancer at Zhongshan Hospital. We assessed patients who underwent additional surgery following the prior non-curative endoscopic resection (n = 145) and patients who underwent radical surgery directly (n = 336). There was no significant difference in 5-year OS (99.3% vs. 99.4%, P = 0.866) and 5-year DFS (97.2% vs. 97.3%, P = 0.909) between the two groups. The total complication rate was slightly higher in prior endoscopic resection group (15.2% vs. 9.5%, P = 0.111). The 5-year OS and 5-year DFS of patients who refused additional surgery (n = 95) were significantly lower than ER prior to surgery group (For OS, 92.6% vs. 99.3%, P = 0.017; for DFS, 91.2% vs. 97.2%, P = 0.021).

conclusionIn patients who underwent additional surgery, non-curative endoscopic resection of cT1 colorectal carcinoma did not have adverse effect on short-term and long-term outcomes. Additional surgery should be recommended in patients who received non-curative ER.

Indexed as

Colorectal NeoplasmsEndoscopyHumansPrognosisReoperationRetrospective StudiesTreatment OutcomeAdditional surgeryLong-term outcomeNon-curative endoscopic resectionT1 colorectal carcinoma

Identifiers

PMID32613303
OpenAlexW3040411310

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.