ReviewMolecular diagnosis & therapy2020
Importance of Identifying Novel Biomarkers of Microvascular Damage in Type 1 Diabetes.
Review in Molecular diagnosis & therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of the association of Type I diabetes with sensorineural hearing loss.PloS one · 2024Pooled it
- Development and validation of a predictive risk model based on retinal geometry for an early assessment of diabetic retinopathy.Frontiers in endocrinology · 2022Trial
- The differential effects of dyslipidemia status and triglyceride-glucose index on left ventricular global function and myocardial microcirculation in diabetic individuals: a cardiac magnetic resonance study.Cardiovascular diabetology · 2024Article
- Early left ventricular microvascular dysfunction in diabetic pigs: a longitudinal quantitative myocardial perfusion CMR study.Cardiovascular diabetology · 2024Article
- Retinal Oxygen Metabolism in Patients With Type 2 Diabetes and Different Stages of Diabetic Retinopathy.Diabetes · 2022Article
- A Contemporary Insight of Metabolomics Approach for Type 1 Diabetes: Potential for Novel Diagnostic Targets.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Review
- Neuro-vascular coupling and heart rate variability in patients with type II diabetes at different stages of diabetic retinopathy.Frontiers in medicine · 2022Article
- Metabolomics in Retinal Diseases: An Update.Biology · 2021Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microvascular complications of type 1 diabetes, which primarily include diabetic kidney disease, retinopathy, and neuropathy, are characterized by damage to the microvasculature of the kidney, retina, and neurons. The pathogenesis of these complications is multifactorial, and several pathways are implicated. These complications are often silent during their early stages, and once symptoms develop, there might be little to be done to cure them. Thus, there is a strong need for novel biomarkers to identify individuals at risk of microvascular complications at an early stage and guide the implementation of new therapeutic options for preventing their development and progression. Recent advancements in proteomics, metabolomics, and other 'omics' have led to the identification of several potential biomarkers of microvascular complications. However, biomarker discovery has met several challenges and, up to now, there are no new biomarkers that have been implemented into clinical practice. This highlights the need for further work in this area to move towards better diagnostic and prognostic approaches.
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Registered trials
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