Evidence map›Paper›PMID 32613075›Full record

ArticleSSM - population health2020

Opioid agonist therapy trajectories among street entrenched youth in the context of a public health crisis.

Valerie Giang, Madison Thulien, Ryan McNeil, Kali Sedgemore, Haleigh Anderson, Danya Fast

Open access · goldAbstract read
In one paragraph

Article in SSM - population health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
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  7. Review
  8. Medications for Opioid Use Disorder for Youth: Patient, Caregiver, and Clinician Perspectives.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2024
    Article
  9. Article
  10. Article
  11. Methadone Maintenance Treatment Discontinuation Among Young People who use Opioids in Vancouver, Canada.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2023
    Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Valerie GiangBritish Columbia Centre on Substance Use, Vancouver, Canada.
Madison ThulienBritish Columbia Centre on Substance Use, Vancouver, Canada.
Ryan McNeilYale School of Medicine, New Haven, USA.
Kali SedgemoreBritish Columbia Centre on Substance Use, Vancouver, Canada.
Haleigh AndersonBritish Columbia Centre on Substance Use, Vancouver, Canada.
Danya FastBritish Columbia Centre on Substance Use, Vancouver, Canada.
British Columbia Centre on Substance Use · CAUniversity of British Columbia · CAYale University · US

Funding

An ethno-epidemiological study of the implementation and effectiveness of an innovative and comprehensive response to the opioid epidemicR01DA044181 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI Thomas Kerr, Ryan McNeil · 2017 to 2026
$4.0M
Mentoring the next generation of addiction clinician scientists while responding to the opioid epidemicR25DA037756 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI FAIRBAIRN, NADIA · 2014 to 2023
$3.6M
NIDA NIH HHS R01 DA044181NIDA NIH HHS R25 DA037756
6 · The paper itself

Abstract

North America is in the midst of an overdose crisis that is having devastating effects among street entrenched youth (<30 years of age). Opioid agonist therapy (OAT) is a cornerstone of the public health response to this crisis; yet, we struggle to connect youth to OAT across numerous settings. This qualitative study examined perspectives on OAT among street entrenched youth and their providers in Vancouver, Canada. Our findings reveal youth's hopes and fears surrounding making a "full" recovery from past substance use. Youth often equated getting off opioids with "getting back to normal" and the ability to pursue "normal" kinds of futures. While many initiated OAT for short periods of time (<one month) to mediate the discomfort of withdrawal during in-patient treatment, adherence to medications like methadone and buprenorphine over the longer term did not fit with many youth's visions of "normal" futures. A number of polysubstance using youth did not access OAT, despite its lifesaving potential. Youth who did access OAT often preferred methadone because of its perceived ability to mediate longstanding physical and mental health issues. Participants who accessed OAT had the most success with adherence when they were invested in this treatment modality and actively involved in decision making around what kind of medication would work best for them, and for how long. In the absence of this collaboration, many youth made the decision to taper off of OAT independently, frequently resulting in relapse and heightened overdose risk.

Indexed as

North AmericaOpioid agonist therapyOpioid use disorderOverdoseStreet entrenched youthSubstance use disorder

Identifiers

PMID32613075
PMCPMC7317668
OpenAlexW3033175269

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.