ArticleFrontiers in cell and developmental biology2020
Plasma Metabolic Profiling of Human Thyroid Nodules by Gas Chromatography-Mass Spectrometry (GC-MS)-Based Untargeted Metabolomics.
Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 52 citations in OpenAlex.
- Different fatty acid patterns in serum in patients with various thyroid diseases.Scientific reports · 2026Article
- Thyroid cancer: From molecular insights to therapy (Review).Oncology letters · 2025Review
- Metabolomics fingerprinting of thyroid malignancies: a GC/MS-based approach for subtype classification and biomarker discovery.BMC cancer · 2025Article
- Towards an Integrated Multi-Omic Approach to Improve the Diagnostic Accuracy of Fine-Needle Aspiration in Thyroid Nodules with Indeterminate Cytology.Diagnostics (Basel, Switzerland) · 2025Review
- Systems biology approach delineates critical pathways associated with papillary thyroid cancer: a multi-omics data analysis.Thyroid research · 2025Article
- Omics experiments in Iran, a review in endocrine and metabolism disorders studies.Journal of diabetes and metabolic disorders · 2024Review
- Detection and Validation of Organic Metabolites in Urine for Clear Cell Renal Cell Carcinoma Diagnosis.Metabolites · 2024Article
- The Role of Lipid Metabolism Disorders in the Development of Thyroid Cancer.International journal of molecular sciences · 2024Review
- Metabolic Profiles and Blood Biomarkers to Discriminate between Benign Thyroid Nodules and Papillary Carcinoma, Based on UHPLC-QTOF-ESIInternational journal of molecular sciences · 2024Article
- Profiling of endogenous metabolites and changes in intestinal microbiota distribution after GEN-001 (The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2024Article
- Non-Targeted Metabolomics Investigation of a Sub-Chronic Variable Stress Model Unveils Sex-Dependent Metabolic Differences Induced by Stress.International journal of molecular sciences · 2024Article
- Prediction of positive pulmonary nodules based on machine learning algorithm combined with central carbon metabolism data.Journal of cancer research and clinical oncology · 2024Article
- Article
- Exploring the potential of myo-inositol in thyroid disease management: focus on thyroid cancer diagnosis and therapy.Frontiers in endocrinology · 2024Review
- Combined metabolomic and lipidomic analysis uncovers metabolic profile and biomarkers for papillary thyroid carcinoma.Scientific reports · 2023Article
- Experimental study on changes in metabolic mechanism of papillary thyroid carcinoma complicated with Hashimoto's thyroiditis.Heliyon · 2023Article
- Auxiliary Diagnosis of Papillary Thyroid Carcinoma Based on Spectral Phenotype.Phenomics (Cham, Switzerland) · 2023Article
- Diagnostic Value of Salivary Amino Acid Levels in Cancer.Metabolites · 2023Review
- Alterations in the amino acid profile in patients with papillary thyroid carcinoma with and without Hashimoto's thyroiditis.Frontiers in endocrinology · 2023Article
- Targeted metabolomics reveals the association between central carbon metabolism and pulmonary nodules.PloS one · 2023Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the challenges in the area of diagnostics of human thyroid cancer is a preoperative diagnosis of thyroid nodules with indeterminate cytology. Herein, we report an untargeted metabolomics analysis to identify circulating thyroid nodule metabolic signatures, to find new novel metabolic biomarkers. Untargeted gas chromatography-quadrupole-mass spectrometry was used to ascertain the specific plasma metabolic changes of thyroid nodule patients, which consisted of papillary thyroid carcinoma (PTC;
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