ArticleFrontiers in pediatrics2020
Factors Associated With the Development of Chronic Kidney Disease in Children With Congenital Anomalies of the Kidney and Urinary Tract.
Article in Frontiers in pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29 citing papers in PubMed, 44 citations in OpenAlex.
- Screening of pediatric patients with congenital anomalies of the kidney and urinary tract for associated congenital heart disease in a tertiary care setting.Pediatric nephrology (Berlin, Germany) · 2026Article
- The epidemiology of kidney and urinary tract infections in pediatric chronic kidney disease: prevalence, risk factors and association with GFR decline in the Chronic Kidney Disease in Children Study.Pediatric nephrology (Berlin, Germany) · 2026Article
- Risk factors for chronic kidney disease progression in VACTERL-association Korean patients: a retrospective study.Childhood kidney diseases · 2026Article
- Chronic Kidney Disease in Children with Suspected Genetic Etiology: Diagnostic Yield and Clinical Implications.Journal of personalized medicine · 2026Article
- Congenital Anomalies of Kidney and Urinary Tract in Children - Clinical Spectrum and Complications.Indian journal of pediatrics · 2026Article
- Pediatric Dialysis: From Acute Kidney Injury to Chronic Renal Replacement Therapies: Challenges and Perspectives in Resource-Limited Countries.Diseases (Basel, Switzerland) · 2026Review
- Temporal trends and projections in the global burden of congenital genitourinary anomalies from 1990 to 2021: A cross-sectional study.The Journal of international medical research · 2026Article
- Chronic Kidney Disease in Lithuanian Children: Single Center Experience.Acta medica Lituanica · 2026Article
- Burden of chronic kidney disease among children and adolescents in the South-East Asia and Western Pacific regions, 1990 to 2021.International journal of public health · 2026Article
- Risk factors for perinatal and neonatal mortality in cases with congenital anomalies of the kidney and urinary tract: a nested cohort study.Pediatric nephrology (Berlin, Germany) · 2025Article
- Renal dysplasia development and chronic kidney disease.Pediatric research · 2025Review
- Article
- Kidney Transplantation in Congenital Abnormalities of Kidney and Urinary Tract (CAKUT).Biomedicines · 2025Review
- Burden of urogenital congenital anomalies: findings from the global burden of disease study 2021.Frontiers in pediatrics · 2025Article
- Maternal and fetal risk factors for congenital anomalies of the kidney and urinary tract: a birth cohort study in urban China.Journal of nephrology · 2024Article
- Maternal diseases and congenital anomalies of the kidney and urinary tract in offspring: a cohort study.World journal of pediatrics : WJP · 2024Article
- Genetic and Clinical Factors Influencing Congenital Anomalies of the Kidney and Urinary Tract in Children: Insights from Prenatal and Postnatal Assessments.Biomedicines · 2024Article
- Maternal periconceptional folic acid supplementation and risk for fetal congenital genitourinary system defects.Pediatric research · 2024Article
- Spectrum of congenital anomalies of the kidney and urinary tract in a pediatric nephrology clinic in Ethiopia and factors associated with advanced chronic kidney disease: A cross-sectional study.PLOS global public health · 2024Article
- Associations between PMFrontiers in public health · 2024Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Congenital anomalies of the kidney and urinary tract (CAKUT) are the most common cause of end-stage renal disease in children and adolescents. The diversity of the malformations summarized by CAKUT is high and there are numerous associated syndromes. The genetic background of these malformations remains unknown in the majority of cases. The aim of this study was to evaluate factors associated with the development of chronic kidney disease (CKD) and underlying genetic aberrations in children and adolescents with CAKUT. For this purpose, data from patients with CAKUT presented at the pediatric nephrology outpatient clinic were analyzed in a cross-sectional single-center study. Among the 405 patients, the commonest findings related to CAKUT were renal hypoplasia/dysplasia (65%), followed by hydronephrosis (43%). Forty-four percent of the patients were suffering from CKD, 6% were ranked as end-stage renal disease. In the univariate analysis, male gender and premature birth were associated with higher CKD stages (
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