Evidence map›Paper›PMID 32612608›Full record

ArticleFrontiers in immunology2020

Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers.

Diane G Carnathan, Kirti Kaushik, Ali H Ellebedy, Chiamaka A Enemuo, Etse H Gebru, Pallavi Dhadvai, Mohammed Ata Ur Rasheed, Matthias G Pauthner, Gabriel Ozorowski, Rafi Ahmed and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Naive and memory CD4iScience · 2022
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Diane G CarnathanYerkes National Primate Research Center, Emory University, Atlanta, GA, United States.
Kirti KaushikCenter for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA, United States.
Ali H EllebedyEmory Vaccine Center, School of Medicine, Emory University, Atlanta, GA, United States.
Chiamaka A EnemuoYerkes National Primate Research Center, Emory University, Atlanta, GA, United States.
Etse H GebruYerkes National Primate Research Center, Emory University, Atlanta, GA, United States.
Pallavi DhadvaiYerkes National Primate Research Center, Emory University, Atlanta, GA, United States.
Mohammed Ata Ur RasheedEmory Vaccine Center, School of Medicine, Emory University, Atlanta, GA, United States.
Matthias G PauthnerScripps Center for HIV/AIDS Vaccine Immunogen Development (CHAVD), The Scripps Research Institute, La Jolla, CA, United States.
Gabriel OzorowskiScripps Center for HIV/AIDS Vaccine Immunogen Development (CHAVD), The Scripps Research Institute, La Jolla, CA, United States.
Rafi AhmedEmory Vaccine Center, School of Medicine, Emory University, Atlanta, GA, United States.
Dennis R BurtonScripps Center for HIV/AIDS Vaccine Immunogen Development (CHAVD), The Scripps Research Institute, La Jolla, CA, United States.
Andrew B WardScripps Center for HIV/AIDS Vaccine Immunogen Development (CHAVD), The Scripps Research Institute, La Jolla, CA, United States.
Guido SilvestriYerkes National Primate Research Center, Emory University, Atlanta, GA, United States.
Shane CrottyScripps Center for HIV/AIDS Vaccine Immunogen Development (CHAVD), The Scripps Research Institute, La Jolla, CA, United States.
Michela LocciScripps Center for HIV/AIDS Vaccine Immunogen Development (CHAVD), The Scripps Research Institute, La Jolla, CA, United States.
Emory University · USScripps Research Institute · USLa Jolla Institute for Immunology · USWashington University in St. Louis · US

Funding

Identification of neutralizing epitopes on SARS-CoV-2 spike for design of vaccines and small-molecule antiviralsUM1AI144462 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI BURTON, DENNIS R. · 2019 to 2025
$201.6M
Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Support Component D/Vaccine Discovery, Concept to ClinicUM1AI100663 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI MCELRATH, MARGARET JULIANA · 2012 to 2018
$131.5M
YNPRC NHP CLINICAL MEDICINE RESIDENCY PROGRAM - SUPPLEMENTP51RR000165 · NCRR · EMORY UNIVERSITY · PI ALTMAN, JOHN DAVID · 1985 to 2011
$114.0M
Maximizing germinal centers and somatic hypermutation to HIV Env immunogensR01AI125068 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROTTY, SHANE P, IRVINE, DARRELL J · 2016 to 2020
$4.3M
Cytokine regulation of T follicular helper (Tfh) cell biologyR01AI123738 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI LOCCI, MICHELA · 2017 to 2021
$2.0M
NCRR NIH HHS P51 RR000165NIAID NIH HHS R01 AI123738NIAID NIH HHS R01 AI125068NIAID NIH HHS UM1 AI100663NIAID NIH HHS UM1 AI144462NIH HHS P51 OD011132
6 · The paper itself

Abstract

T follicular helper (T

Indexed as

Adjuvants, ImmunologicActivinsAIDS VaccinesAnimalsAntibody FormationDisease Models, Animalenv Gene Products, Human Immunodeficiency VirusHIV-1HIV AntibodiesHIV InfectionsHumansImmunizationImmunization ScheduleImmunophenotypingMacaca mulattaMaleactivin AActivinsAdjuvants, ImmunologicAIDS Vaccinesenv Gene Products, Human Immunodeficiency VirusHIV Antibodiesantibody longevityB cellsHIVT follicular helper cellsT follicular regulatory cellsvaccine

Identifiers

PMID32612608
PMCPMC7308430
OpenAlexW3035011647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.