Evidence map›Paper›PMID 32612568›Full record

ArticleFrontiers in neurology2020

Anti-Dopamine Receptor 2 Antibody-Positive Encephalitis in Adolescent.

Xuejiao Dai, Lilu Kuang, Li Feng, Xiaoping Yi, Weiting Tang, Qiao Liao, Xiaoyan Long, Junling Wang, Jing Li, Huan Yang and 3 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Decoding Dystonia in Autoimmune Disorders: A Scoping Review.Tremor and other hyperkinetic movements (New York, N.Y.) · 2024
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Xuejiao DaiDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Lilu KuangDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Li FengDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Xiaoping YiDepartment of Radiology, Xiangya Hospital, Central South University, Changsha, China.
Weiting TangDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Qiao LiaoDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Xiaoyan LongDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Junling WangDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Jing LiDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Huan YangDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Bo XiaoDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Guoliang LiDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Si ChenDepartment of Neurology, Xiangya Hospital, Central South University, Changsha, China.
Central South University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune encephalitic syndromes include mutism, somnolence, movement disorder, and behavioral, or psychiatric symptoms. When paired with bilateral basal ganglia lesions on magnetic resonance imaging, these support the diagnosis of basal ganglia encephalitis (BGE). BGE is a rare but distinct entity of putative autoimmune etiology, with specific basal ganglia inflammation and acute movement disorders. A previous study identified dopamine-2 receptors (D2R) antibody to be positive in most BGE children, indicating that the D2R antibody may trigger the downstream pathological process in BGE patients. The highest levels of D2R are found in the striatum, the nucleus accumbens, and the olfactory tubercle. D2R antibody-positive BGE is widely reported in children. Here we present a 17-year-old girl with a typical clinical feature of basal ganglia encephalitis, who benefited from immune therapy.

Indexed as

adolescentbasal ganglia encephalitisD2Rmovement disorderpsychiatric

Identifiers

PMID32612568
PMCPMC7308480
OpenAlexW3026353761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.