Evidence map›Paper›PMID 32612545›Full record

ArticleFrontiers in psychiatry2020

Sexual Abuse in Adolescents Is Associated With Atypically Increased Responsiveness Within Regions Implicated in Self-Referential and Emotional Processing to Approaching Animate Threats.

Karina S Blair, Johannah Bashford-Largo, Niraj Shah, Jennie Lukoff, Jaimie Elowsky, Steven Vogel, Amanda Emmert, Ru Zhang, Matthew Dobbertin, Seth Pollak and 1 more

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. A Shared Multivariate Brain-Behavior Relationship in a Transdiagnostic Sample of Adolescents.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Karina S BlairCenter for Neurobehavioral Research, Boys Town National Research Hospital, Boys Town, NE, United States.
Johannah Bashford-LargoCenter for Neurobehavioral Research, Boys Town National Research Hospital, Boys Town, NE, United States.
Niraj ShahCenter for Neurobehavioral Research, Boys Town National Research Hospital, Boys Town, NE, United States.
Jennie LukoffCenter for Neurobehavioral Research, Boys Town National Research Hospital, Boys Town, NE, United States.
Jaimie ElowskyCenter for Neurobehavioral Research, Boys Town National Research Hospital, Boys Town, NE, United States.
Steven VogelCenter for Neurobehavioral Research, Boys Town National Research Hospital, Boys Town, NE, United States.
Amanda EmmertDepartment of Psychiatry, Creighton University School of Medicine, Omaha, NE, United States.
Ru ZhangCenter for Neurobehavioral Research, Boys Town National Research Hospital, Boys Town, NE, United States.
Matthew DobbertinCenter for Neurobehavioral Research, Boys Town National Research Hospital, Boys Town, NE, United States.
Seth PollakDepartment of Psychology, University of Wisconsin, Madison, WI, United States.
James R BlairCenter for Neurobehavioral Research, Boys Town National Research Hospital, Boys Town, NE, United States.

Funding

Emotion Processing:Risk for Psychopathology in ChildrenR01MH061285 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI SETH D POLLAK · 2001 to 2026
$12.4M
Acute threat and frustrative non-reward components of irritability and reactive aggressionK22MH109558 · NIMH · FATHER FLANAGAN'S BOYS' HOME · PI BLAIR, JAMES · 2016 to 2018
$972k
NIMH NIH HHS K22 MH109558NIMH NIH HHS R01 MH061285
6 · The paper itself

Abstract

Childhood sexual abuse is associated with significant subsequent pathology and neurodevelopmental disruption. In particular, childhood sexual abuse has been associated with heightened threat sensitivity. However, little work has directly investigated this issue. In this study, we examine the association of childhood sexual abuse to neural and behavioral responses to looming, threatening face stimuli. The study involved 23 adolescents with significant past sexual abuse and 24 comparison individuals matched on IQ, age, and sex. Participants were scanned during a looming threat task that involved negative and neutral, human faces and animals that appeared to either loom toward or recede from the participant. We found that adolescents who had been previously subjected to sexual abuse, relative to comparison adolescents, showed increased neural responses to

Indexed as

adolescentschildhood sexual abusefunctional Magnetic Resonance Imaging (fMRI)looming threatthreat responsiveness

Identifiers

PMID32612545
PMCPMC7308525

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.