ArticleClinical, cosmetic and investigational dentistry2020
Review of Etiology of Posterior Open Bite: Is There a Possible Genetic Cause?
Article in Clinical, cosmetic and investigational dentistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Effects of tongue tamers and customized bonded spurs as an early treatment of anterior open bite: a randomized clinical study.BMC oral health · 2025Trial
- Frequency and skeletal factors associated with posterior open bite during oral appliance therapy for obstructive sleep apnea: A retrospective study.Sleep & breathing = Schlaf & Atmung · 2026Article
- Influence of different malocclusion traits on overall orthodontic treatment duration.The Angle orthodontist · 2026Article
- Case Report: A comparative evaluation of anterior open bite orthodontic treatment outcomes and stability of results in monozygotic twins.Frontiers in oral health · 2026Article
- Mechanisms of primary failure of eruption: a new model of multidimensional framework.Progress in orthodontics · 2025Review
- Permanent first molar eruption failure in children: leading signs for early diagnosis.Progress in orthodontics · 2025Observational
- Primary Failure of Eruption: A Rare but Desperate Condition for Orthodontic Treatment.Turkish journal of orthodontics · 2025Article
- Tongue Behavior in Anterior Open Bite-A Narrative Review.Diagnostics (Basel, Switzerland) · 2025Review
- Short- and Long-Term Effects of Maxillary Expander with Tongue Crib in Growing Open-Bite and Skeletal Class II Patients: A Retrospective Study.Dentistry journal · 2024Article
- Anterior Open Bite Malocclusion: From Clinical Treatment Strategies towards the Dissection of the Genetic Bases of the Disease Using Human and Collaborative Cross Mice Cohorts.Journal of personalized medicine · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Posterior open bite (POB) is one of the most severe malocclusions that can impair patients' masticatory functions, yet it is also a condition that is poorly understood and not well studied. Most reported cases are either sporadic or idiosyncratic with a diverse yet poorly understood etiology. Although primary failure of eruption (PFE), lateral tongue thrust, and certain medical syndromes or pathology of the temporomandibular joints have all been shown to cause POB, the complex interplay of environmental and genetic factors makes its etiopathogenesis a difficult subject to understand and investigate. Here, we provide a comprehensive review of the etiology of posterior open bite. Additionally, a genetic cause for POB is proposed through a report of an apparently non-syndromic familial case series with high POB penetrance across two generations. Further investigations of the gene(s) and mechanism(s) involved can not only provide a unique opportunity to better understand POB and the intricate muscular-occlusal relationship, but also offer powerful insight into the most effective approaches to clinical management of these (and potentially other) malocclusions.
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