Evidence map›Paper›PMID 32612317›Full record

ArticleSurface & coatings technology2020

Effects of vitamin C on osteoblast proliferation and osteosarcoma inhibition using plasma coated hydroxyapatite on titanium implants.

Naboneeta Sarkar, Hailey Morton, Susmita Bose

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surface & coatings technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Role of vitamins in the development and treatment of osteoporosis (Review).International journal of molecular medicine · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Natural medicine delivery from 3D printed bone substitutes.Journal of controlled release : official journal of the Controlled Release Society · 2024
    Review
  8. Hydroxyapatite Biobased Materials for Treatment and Diagnosis of Cancer.International journal of molecular sciences · 2022
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Naboneeta SarkarW. M. Keck Biomedical Materials Research Laboratory School of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, United States.
Hailey MortonW. M. Keck Biomedical Materials Research Laboratory School of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, United States.
Susmita BoseW. M. Keck Biomedical Materials Research Laboratory School of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, United States.
Washington State University · US

Funding

Surface modified metal implants using doped hydroxyapatiteR01AR066361 · NIAMS · WASHINGTON STATE UNIVERSITY · PI BOSE, SUSMITA · 2014 to 2018
$1.6M
NIAMS NIH HHS R01 AR066361
6 · The paper itself

Abstract

Plasma-sprayed hydroxyapatite (HAp) coated titanium (Ti) implants are being extensively used in orthopedic surgeries and post-tumor resection to repair load-bearing segmental bone defects. In this study, vitamin C, an abundantly available natural biomolecule, is loaded onto plasma-sprayed HAp-coated commercially pure titanium (cpTi) surface to evaluate its chemopreventive and osteogenic properties, suggesting its clinical significance as an alternative or adjunct therapy in the treatment for osteosarcoma bone resection. Controlled release of vitamin C from HAp coated cpTi implant is assessed by

Indexed as

In vitro vitamin C releaseload-bearing Ti implantOsteoblast cell cultureOsteosarcoma cell culturePlasma coated HAp

Identifiers

PMID32612317
PMCPMC7328859
OpenAlexW3017272408

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.