Evidence map›Paper›PMID 32612253›Full record

ArticleScientific reports2020

Conservation and divergence in NaChBac and Na

Wandi Zhu, Tianbo Li, Jonathan R Silva, Jun Chen

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wandi ZhuBiochemical and Cellular Pharmacology, Genentech Inc., 103 DNA Way, South San Francisco, CA, USA. wzhu5@bwh.harvard.edu.
Tianbo LiBiochemical and Cellular Pharmacology, Genentech Inc., 103 DNA Way, South San Francisco, CA, USA.
Jonathan R SilvaBiomedical Engineering, Washington University in St. Louis, St. Louis, MO, USA.
Jun ChenBiochemical and Cellular Pharmacology, Genentech Inc., 103 DNA Way, South San Francisco, CA, USA. chen.jun@gene.com.

Funding

MODULATION OF CARDIAC NAV CHANNEL FUNCTION AND ELECTROPHYSIOLOGY BY INTERACTING MOLECULESR01HL136553 · NHLBI · WASHINGTON UNIVERSITY · PI SILVA, JONATHAN R · 2017 to 2021
$1.9M
NHLBI NIH HHS R01 HL136553NIH HHS HL136553
6 · The paper itself

Abstract

Voltage-gated Na

Indexed as

Drug InteractionsAconitineAnesthetics, LocalBacterial ProteinsElectrophysiological PhenomenaHEK293 CellsHumansIon Channel GatingNAV1.7 Voltage-Gated Sodium ChannelSmall Molecule LibrariesSodium ChannelsToxins, BiologicalVeratridineVoltage-Gated Sodium Channel AgonistsAconitineAnesthetics, LocalBacterial ProteinsNaChBac protein, bacteriaNAV1.7 Voltage-Gated Sodium ChannelSCN9A protein, humanSmall Molecule LibrariesSodium ChannelsToxins, BiologicalVeratridineVoltage-Gated Sodium Channel Agonists

Identifiers

PMID32612253
PMCPMC7329812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.