Evidence map›Paper›PMID 32612191›Full record

ArticleScientific reports2020

Global analysis of protein degradation in prion infected cells.

Charles R Hutti, Kevin A Welle, Jennifer R Hryhorenko, Sina Ghaemmaghami

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. New Therapeutic Modalities in Prion Diseases.Sub-cellular biochemistry · 2025
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Charles R HuttiDepartment of Biology, University of Rochester, New York, 14627, USA.
Kevin A WelleUniversity of Rochester Mass Spectrometry Resource Laboratory, New York, 14627, USA.
Jennifer R HryhorenkoUniversity of Rochester Mass Spectrometry Resource Laboratory, New York, 14627, USA.
Sina GhaemmaghamiDepartment of Biology, University of Rochester, New York, 14627, USA. sina.ghaemmaghami@rochester.edu.
University of Rochester · US

Funding

The prevalence and mechanism of selectivity in basal autophagyR35GM119502 · NIGMS · UNIVERSITY OF ROCHESTER · PI SINA GHAEMMAGHAMI · 2016 to 2026
$5.9M
Orbitrap Fusion Lumos Mass Spectrometer for UR Proteomics ResearchS10OD025242 · OD · UNIVERSITY OF ROCHESTER · PI GHAEMMAGHAMI, SINA · 2018 to 2018
$1.1M
NIH HHS GM119502-1230 01NIH HHS S10 OD025242
6 · The paper itself

Abstract

Prion diseases are rare, neurological disorders caused by the misfolding of the cellular prion protein (PrP

Indexed as

ProteolysisCell Line, TumorHumansPrion DiseasesProteomeProteomicsPrPSc ProteinsProteomePrPSc Proteins

Identifiers

PMID32612191
PMCPMC7329860
OpenAlexW3039858223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.