Evidence map›Paper›PMID 32612106›Full record

ArticleCell death and differentiation2020

MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3

Charis E Teh, Alissa K Robbins, Darren C Henstridge, Grant Dewson, Sarah T Diepstraten, Gemma Kelly, Mark A Febbraio, Sarah S Gabriel, Lorraine A O'Reilly, Andreas Strasser and 1 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell death and differentiation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Charis E Teh *The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC, Australia.
Alissa K Robbins *The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC, Australia.
Darren C HenstridgeCellular and Molecular Metabolism Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Grant DewsonThe Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC, Australia.
Sarah T DiepstratenThe Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC, Australia.ORCID http://orcid.org/0000-0002-1946-5161
Gemma KellyThe Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC, Australia.
Mark A FebbraioCellular and Molecular Metabolism Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
Sarah S GabrielThe Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia.
Lorraine A O'ReillyThe Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC, Australia.
Andreas StrasserThe Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC, Australia.
Daniel H D GrayThe Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC, Australia. dgray@wehi.edu.au.ORCID http://orcid.org/0000-0002-8457-8242
The University of Melbourne · AUBaker Heart and Diabetes Institute · AUUniversity of Tasmania · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

FOXP3

Indexed as

AnimalsApoptosisCell SurvivalFemaleForkhead Transcription FactorsGene DeletionHomeostasisImmune ToleranceMaleMiceMice, Inbred C57BLMice, KnockoutMyeloid Cell Leukemia Sequence 1 ProteinSignal TransductionT-Lymphocytes, RegulatoryForkhead Transcription FactorsFoxp3 protein, mouseMcl1 protein, mouseMyeloid Cell Leukemia Sequence 1 Protein

Identifiers

PMID32612106
PMCPMC7853142
OpenAlexW3039016765

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.