Evidence map›Paper›PMID 32611955›Full record

ArticleInternal medicine (Tokyo, Japan)2020

Regression and Stabilization of Coronary Vulnerable Plaque by Evolocumab as Assessed by Multidetector Row Computed Tomography.

Yuhei Shiga, Yoshiaki Idemoto, Kohei Tashiro, Tomoki Imaizumi, Yoko Ueda, Yuiko Yano, Kenji Norimatsu, Ayumi Nakamura, Shin-Ichiro Miura

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuhei ShigaDepartment of Cardiology, Fukuoka University School of Medicine, Japan.
Yoshiaki IdemotoDepartment of Cardiology, Fukuoka University School of Medicine, Japan.
Kohei TashiroDepartment of Cardiology, Fukuoka University School of Medicine, Japan.
Tomoki ImaizumiDepartment of Cardiology, Fukuoka University School of Medicine, Japan.
Yoko UedaDepartment of Cardiology, Fukuoka University School of Medicine, Japan.
Yuiko YanoDepartment of Cardiology, Fukuoka University School of Medicine, Japan.
Kenji NorimatsuDepartment of Cardiology, Fukuoka University School of Medicine, Japan.
Ayumi NakamuraDepartment of Cardiology, Fukuoka University School of Medicine, Japan.
Shin-Ichiro MiuraDepartment of Cardiology, Fukuoka University School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 65-year-old man was followed for his coronary conditions using 320-multi detector row computed tomography (MDCT) for 30 months. He had soft plaque in the right coronary artery (RCA) [mean density of plaque was 22 hounsfield units (HU)]. His initial serum low-density lipoprotein cholesterol (LDL-C) was 72 mg/dL. After 30 months, his serum LDL-C was 26 mg/dL under 5.0 mg/day rosuvastatin and evolocumab 140 mg/2 weeks. MDCT showed a regression of the plaque in the RCA and the plaque density was 114 HU (intermediate plaque). In conclusion, intensive lipid-lowering therapy with evolocumab induced the regression and stabilization of coronary vulnerable plaque.

Indexed as

AgedAntibodies, Monoclonal, HumanizedCoronary Artery DiseaseCoronary VesselsHumansMaleMultidetector Computed TomographyPlaque, AmyloidPlaque, AtheroscleroticTreatment OutcomeAntibodies, Monoclonal, Humanizedevolocumabmultidetector row computed tomographymyocardial infarctionPCSK9plaque

Identifiers

PMID32611955
PMCPMC7644491

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.