Evidence map›Paper›PMID 32611954›Full record

ArticleInternal medicine (Tokyo, Japan)2020

Low-dose Selective Arterial Calcium Stimulation Test for Localizing Insulinoma: A Single-center Experience of Five Consecutive Cases.

Tomonobu Hatoko, Takaaki Murakami, Masakatsu Sone, Daisuke Yabe, Toshihiko Masui, Yuji Nakamoto, Akihiro Furuta, Norimitsu Uza, Yuzo Kodama, Norio Harada and 3 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Frontiers in endocrinology · 2023
    Article
  4. Picking up an insulinoma - The challenges ahead.Journal of family medicine and primary care · 2022
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Tomonobu HatokoDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.
Takaaki MurakamiDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.
Masakatsu SoneDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.
Daisuke YabeDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.
Toshihiko MasuiDepartment of Hepato-Biliary-Pancreatic Surgery and Transplantation, Kyoto University Graduate School of Medicine, Japan.
Yuji NakamotoDepartment of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Japan.
Akihiro FurutaDepartment of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Japan.
Norimitsu UzaDepartment of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Japan.
Yuzo KodamaDepartment of Gastroenterology, Kobe University Graduate School of Medicine, Japan.
Norio HaradaDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.
Masahito OguraDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.
Akihiro YasodaDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.
Nobuya InagakiDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.
Kyoto University · JPGifu University · JPKobe University · JPKyoto Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The selective arterial calcium stimulation test (SACST) is one of the most useful localization tests for insulinoma but can cause false-positive and/or unexpected multi arterial positive results that hamper clinical decisions. There are also several adverse effects, such as nausea and hypoglycemia, at the conventional dose (0.025 mEq/kg) of calcium injection. We herein report five consecutive insulinoma cases in which low-dose (0.005-0.007 mEq/kg) calcium injection for SACST led to successful insulinoma localization. No adverse effects of SACST were observed. In conclusion, a low-dose SACST can be a favorable option as an insulinoma localization test in terms of accuracy and safety.

Indexed as

AdultCalciumDose-Response Relationship, DrugFemaleHepatic VeinsHumansInsulinomaJapanMaleMiddle AgedPancreatic NeoplasmsRetrospective StudiesTreatment OutcomeCalciumcalcium stimulationinsulinomalow-doseselective arterial calcium stimulation testselective arterial secretagogue injection test

Identifiers

PMID32611954
PMCPMC7644493
OpenAlexW3039615401

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.