Evidence map›Paper›PMID 32611771›Full record

ArticleThe Journal of biological chemistry2020

TOR complex 2 (TORC2) signaling and the ESCRT machinery cooperate in the protection of plasma membrane integrity in yeast.

Oliver Schmidt, Yannick Weyer, Simon Sprenger, Michael A Widerin, Sebastian Eising, Verena Baumann, Mihaela Angelova, Robbie Loewith, Christopher J Stefan, Michael W Hess and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Oliver SchmidtInstitute for Cell Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria. Electronic address: oliver.schmidt@i-med.ac.at.
Yannick WeyerInstitute for Cell Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Simon SprengerInstitute for Cell Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Michael A WiderinInstitute for Cell Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Sebastian EisingDepartment of Biology/Chemistry, University of Osnabrück, Osnabrück, Germany.
Verena BaumannInstitute for Cell Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Mihaela AngelovaCancer Evolution and Genome Instability Laboratory, Francis Crick Institute, London, United Kingdom.
Robbie LoewithDepartment of Molecular Biology, University of Geneva, Geneva, Switzerland.
Christopher J StefanMRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom.
Michael W HessInstitute for Histology and Embryology, Medical University of Innsbruck, Innsbruck, Austria.
Florian FröhlichDepartment of Biology/Chemistry, University of Osnabrück, Osnabrück, Germany.
David TeisInstitute for Cell Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Innsbruck Medical University · ATOsnabrück University · DEMRC Laboratory for Molecular Cell Biology · GBThe Francis Crick Institute · GBUniversity of Geneva · CH

Funding

Austrian Science Fund FWF P 30263Austrian Science Fund FWF P 32161Medical Research Council MC_UU_00012/6
6 · The paper itself

Abstract

The endosomal sorting complexes required for transport (ESCRT) mediate evolutionarily conserved membrane remodeling processes. Here, we used budding yeast (

Indexed as

Signal TransductionAdenosine TriphosphatasesCell MembraneEndosomal Sorting Complexes Required for TransportGlycogen Synthase Kinase 3Mechanistic Target of Rapamycin Complex 2MutationSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAdenosine TriphosphatasesEndosomal Sorting Complexes Required for TransportGlycogen Synthase Kinase 3MCK1 protein, S cerevisiaeMechanistic Target of Rapamycin Complex 2Orm2 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsVPS4 protein, S cerevisiaecalcineurinendosomal sorting complexes required for transport (ESCRT)endosome and Golgi-associated degradation (EGAD)membranemembrane stressmTOR complex (mTORC)ORMDL familysphingolipidstressTORC2

Identifiers

PMID32611771
PMCPMC7443507
OpenAlexW3038447170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.