Evidence map›Paper›PMID 32611729›Full record

Observational studyStroke and vascular neurology2021

Dynamic contrast-enhanced MRI analysis for prognosis of intracranial dissecting aneurysm with intramural haematoma after endovascular treatment: an observational registry study.

Zhongbin Tian, Zhongxiao Wang, Wenqiang Li, Wei Zhu, Jian Liu, Ying Zhang, Xinjian Yang, Yisen Zhang

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in Stroke and vascular neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03940859 (Investigation of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Analysis Predicting Prognosis of Intracranial Dissecting Aneurysm With Intramural Hematoma After Endovascular Treatment), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03940859 unknown statusnot on this map

Investigation of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Analysis Predicting Prognosis of Intracranial Dissecting Aneurysm With Intramural Hematoma After Endovascular Treatment

Typeobservational_patient_registrySponsorBeijing Neurosurgical InstituteRan2019 to 2021Enrolled80ConditionsDissecting Aneurysm of Cerebral ArteryArmsintracranial stent, flow diverter and coils
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zhongbin TianDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute and Beijing Tian Tan Hospital, Beijing, China.
Zhongxiao WangDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute and Beijing Tian Tan Hospital, Beijing, China.
Wenqiang LiDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute and Beijing Tian Tan Hospital, Beijing, China.
Wei ZhuDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute and Beijing Tian Tan Hospital, Beijing, China.
Jian LiuDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute and Beijing Tian Tan Hospital, Beijing, China.ORCID 0000-0002-5454-2847
Ying ZhangDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute and Beijing Tian Tan Hospital, Beijing, China.
Xinjian YangDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute and Beijing Tian Tan Hospital, Beijing, China.
Yisen ZhangDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute and Beijing Tian Tan Hospital, Beijing, China zhangyisen@bjtth.org.ORCID 0000-0002-8337-9882
Beijing Tian Tan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeIntracranial dissecting aneurysm (IDA) with intramural haematoma (IMH) is an intractable cerebrovascular disease. The outcome of IDA with IMH after endovascular treatment varies across different individuals: some IMHs stop growing after endovascular treatment, while others continue to grow, even after embolisation of the parent artery. Currently, the mechanism for the continuous growth of IMH after endovascular treatment is still unclear. Continuous haemorrhage of the vasa vasorum in the IMH is considered to be associated with continuous enlargement of the IMH; however, this theory has not been proved by in vivo imaging. METHODS AND ANALYSIS: This study will establish a prospective cohort of 80 patients who had an IDA with IMH and received endovascular treatment. Demographic characteristics, IDA morphological characteristics and treatment characteristics will be collected prospectively. All patients will undergo dynamic contrast-enhanced MRI (DCE-MRI) before and 6 months after the endovascular treatment. According to the follow-up results of the MRI, the IDAs will be divided into two groups: a haematoma stabilisation group and a haematoma enlargement group. Then, quantitative analysis of the vasa vasorum in the IMH will be performed, and differences between the two groups will be compared with determine the association between DCE-MRI related parameters and the outcomes of IMH changes. ETHICS AND DISSEMINATION: The research was approved by the ethics committee of Beijing Tian Tan Hospital (KY 2019-024-03) and written informed consents would be obtained from all patients included in this study. The results of this study will be disseminated in professional printed media. TRIAL REGISTRATION NUMBER: NCT03940859. Registered: 7 May, 2019. https://clinicaltrials.gov/ct2/show/NCT03940859.

Indexed as

Aortic DissectionHematomaHumansMagnetic Resonance ImagingPrognosisProspective StudiesRegistriesdissectioninterventionMRI

Identifiers

PMID32611729
PMCPMC8005896
OpenAlexW3038965488

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.