Evidence map›Paper›PMID 32611546›Full record

ArticleBMJ sexual & reproductive health2021

Risk-based screening to identify reproductive tract infection among HIV-infected women desiring use of intrauterine contraceptives.

Nontokozo Langwenya, Catherine S Todd, Heidi E Jones, Donald R Hoover, Nai-Chung Hu, Agnes Ronan, Landon Myer

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ sexual & reproductive health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01721798 (Comparison of Two Intrauterine Devices), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01721798 nacompletednot on this map

Comparison of Two Intrauterine Devices (IUDs) Among Cape Town HIV-positive Women: A Randomized Controlled Trial Assessing Safety of Registered Products in South Africa

TypeinterventionalSponsorFHI 360Ran2013 to 2018Enrolled199ConditionsHIVArmsMirena levonorgestrel IUD, Copper T-380a IUD
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Nontokozo LangwenyaDivision of Epidemiology and Biostatistics, University of Cape Town, Cape Town, South Africa ntokozolangwenya@gmail.com.ORCID 0000-0001-7883-621X
Catherine S ToddGlobal Health, Population, and Nutrition Department, FHI 360, Durham, North Carolina, USA.
Heidi E JonesDepartment of Epidemiology & Biostatistics, City University of New York, New York, New York, USA.
Donald R HooverDepartment of Statistics and Biostatistics, Rutgers University, New Brunswick, New Jersey, USA.
Nai-Chung HuDivision of Epidemiology and Biostatistics, University of Cape Town, Cape Town, South Africa.
Agnes RonanCentre for Infectious Diseases Epidemiology and Research, University of Cape Town, Rondebosch, Western Cape, South Africa.
Landon MyerDivision of Epidemiology and Biostatistics, University of Cape Town, Cape Town, South Africa.
University of Cape Town · ZACity University of New York · USFamily Health International 360 · USRutgers, The State University of New Jersey · US

Funding

Safety and Acceptability of Two IUDs among Cape Town HIV-positive Women: A RCTR01HD071804 · NICHD · FAMILY HEALTH INTERNATIONAL · PI MYER, BENJAMIN LANDON, TODD, CATHERINE SUZANNE · 2012 to 2017
$2.6M
NICHD NIH HHS R01 HD071804
6 · The paper itself

Abstract

backgroundReproductive tract infections (RTIs) are a major cause of morbidity and mortality, yet RTI testing remains limited in resource-constrained settings. We assessed performance of an existing RTI risk assessment screening tool among women living with HIV (WLHIV) considering intrauterine contraceptive (IUC) use.

methodsWe conducted a cross-sectional analysis among WLHIV screened for participation in an IUC trial in Cape Town, South Africa (NCT01721798). RTI testing included

resultsOf 303 women, 52% (n=157) reported antiretroviral therapy use and median age was 31 years. The prevalence of any RTI was 38% (gonorrhoea=7%, chlamydia=11%, trichomoniasis=12% and bacterial vaginosis=18%) and 8% of women had multiple RTIs. Overall, 4%, 27% and 69% of women had screening tool scores of 0, 1 or 2+, respectively. At a threshold of at least one scored criterion, the tool demonstrated high sensitivities (95%-97%) but low specificities (3%-4%) for detecting any RTI. Increasing the score threshold and/or inclusion of abnormal vaginal discharge marginally improved specificity.

conclusionThe prevalence of RTIs observed in this population was high, and the screening tool had no discriminatory power to detect prevalent RTIs.

Indexed as

AdultCross-Sectional StudiesFemaleHIV InfectionsHumansIntrauterine DevicesLogistic ModelsMass ScreeningPrevalenceReproductive Tract InfectionsRisk AssessmentSouth Africacervical screeninghuman immunodeficiency virusintrauterine devicessexually transmitted infections

Identifiers

PMID32611546
PMCPMC8020848
OpenAlexW3038798185

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.