ArticleBMJ (Clinical research ed.)2020
Non-adherence in non-inferiority trials: pitfalls and recommendations.
Article in BMJ (Clinical research ed.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Eradication of Helicobacter pylori With Vonoprazan-Amoxicillin Dual Therapy as an Alternative for Bismuth-Based Quadruple Therapy: A Systematic Review and Noninferiority Meta-Analysis.Journal of gastroenterology and hepatology · 2026Pooled it
- European Stroke Organisation (ESO) guideline on aphasia rehabilitation.European stroke journal · 2025Guideline
- Statistical methods for non-adherence in non-inferiority trials: useful and used? A systematic review.BMJ open · 2022Pooled it
- Trial
- Effectiveness of biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: the BATCH RCT.Health technology assessment (Winchester, England) · 2025Trial
- Seven versus 14 days of antimicrobial therapy for severe multidrug-resistant Gram-negative bacterial infections in intensive care unit patients (OPTIMISE): a randomised, open-label, non-inferiority clinical trial.Critical care (London, England) · 2024Trial
- Trial
- Weaning of maintenance immunosuppressive therapy in lupus nephritis (WIN-Lupus): results of a multicentre randomised controlled trial.Annals of the rheumatic diseases · 2022Trial
- Methods of Analysis in Randomized Noninferiority Trials: Methodological Survey Review Protocol.JMIR research protocols · 2026Article
- Clinical equivalence and non-inferiority within health technology assessment.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Comparison of intention-to-treat and per-protocol results in non-inferiority trials: a methodological review protocol.BMJ open · 2025Article
- Type 2 diabetes, sodium-glucose cotransporter-2 inhibitors and cardiovascular outcomes: real world evidence versus a randomised clinical trial.Cardiovascular diabetology · 2025Article
- Power and sample size calculation for non-inferiority trials with treatment switching in intention-to-treat analysis comparing RMSTs.BMC medical research methodology · 2025Article
- Applying the Estimands Framework to Non-Inferiority Trials: Guidance on Choice of Hypothetical Estimands for Non-Adherence and Comparison of Estimation Methods.Statistics in medicine · 2025Article
- Protocol for visual-acoustic intervention with service delivery in-person and via telepractice (VISIT) non-inferiority trial for residual speech sound disorder.BMC pediatrics · 2025Article
- Non-Inferiority Trials in Stroke Research: What Are They, and How Should We Interpret Them?Journal of stroke · 2025Review
- Methodological Challenges in Randomized Controlled Trials of mHealth Interventions: Cross-Sectional Survey Study and Consensus-Based Recommendations.Journal of medical Internet research · 2024Article
- Key insights and challeneges in noninferiority trials.Korean journal of anesthesiology · 2024Review
- Article
- Effectiveness of a nonweight-based daily dosage of ready-to-use therapeutic food in children suffering from uncomplicated severe acute malnutrition: A nonrandomized, noninferiority analysis of programme data in Afghanistan.Maternal & child nutrition · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.