Evidence map›Paper›PMID 32611265›Full record

ArticleDrug delivery2020

Biological investigations on therapeutic effect of chitosan encapsulated nano resveratrol against gestational diabetes mellitus rats induced by streptozotocin.

Shengye Du, Yan Lv, Na Li, Xianxia Huang, Xuemei Liu, Hui Li, Chao Wang, Yi-Fang Jia

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
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  9. Optimizing antidiabetic properties ofFood science & nutrition · 2024
    Article
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  13. Nanotheranostics: application of nanosensors in diabetes management.Journal of diabetes and metabolic disorders · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Shengye DuDepartment of Obstetrics, Jinan City People's Hospital, Jinan, PR China.
Yan LvGynecological Reproductive Clinic, Jinan City People's Hospital, Jinan, PR China.
Na LiDepartment of Gynecology and Traditional Chinese Medicine, Jinan City People's Hospital, Jinan, PR China.
Xianxia HuangDepartment of Obstetrics, Jinan City People's Hospital, Jinan, PR China.
Xuemei LiuDepartment of Obstetrics, Jinan City People's Hospital, Jinan, PR China.
Hui LiDepartment of Obstetrics, Jinan City People's Hospital, Jinan, PR China.
Chao WangDepartment of Obstetrics, Jinan City People's Hospital, Jinan, PR China.
Yi-Fang JiaCenter of Prenatal Diagnosis, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, PR China.
Jinan City People's Hospital · CNShandong First Medical University · CNShandong Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The chitosan encapsulation with bioactive compounds (resveratrol) is a significant method that can be used to raise the stability and effectiveness of substances in gestational diabetes management. In this study, the resveratrol-zinc oxide complex is encapsulated with chitosan (CS-ZnO-RS). The synthesized CS-ZnO-RS could be used to deliver the resveratrol with minimized side effects and also improved bioavailability. CS-ZnO-RS were characterized by various techniques such as particle size analyzer, DSC, FT-IR, TEM, SEM, and AFM. The electron microscopic and particle analyzer confirmed that the synthesized CS-ZnO-RS were monodispersed, spherical and its average size was 38 nm. The drug-releasing profile showed that 95% of RS is released from CS-ZnO-RS within 24 h.

Indexed as

alpha-AmylasesAnimalsBlood GlucoseChemistry, PharmaceuticalChitosanDiabetes, GestationalDisease Models, AnimalDose-Response Relationship, DrugDrug LiberationFemaleGlycoside Hydrolase InhibitorsInflammation MediatorsMaleNanoparticlesParticle SizePregnancyalpha-AmylasesBlood GlucoseChitosanGlycoside Hydrolase InhibitorsInflammation MediatorsResveratrolStreptozocinZinc Oxidechitosanendoplasmic reticulum stressGestational diabetes mellitusresveratrolstreptozotocin

Identifiers

PMID32611265
PMCPMC8216480
OpenAlexW3038950083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.