Evidence map›Paper›PMID 32610647›Full record

Trial reportNutrients2020

Intermittent Hypoxic Exposure with High Dose of Arginine Impact on Circulating Mediators of Tissue Regeneration.

Agnieszka Zembron-Lacny, Artur Gramacki, Edyta Wawrzyniak-Gramacka, Anna Tylutka, Natalia Hertmanowska, Anna Kasperska, Miłosz Czuba

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Multiple Cryotherapy Attenuates Oxi-Inflammatory Response Following Skeletal Muscle Injury.International journal of environmental research and public health · 2020
    Trial
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Agnieszka Zembron-LacnyDepartment of Applied and Clinical Physiology, Collegium Medicum University of Zielona Gora, 65-417 Zielona Gora, Poland.ORCID 0000-0001-7596-9850
Artur GramackiFaculty of Computer, Electrical and Control Engineering. Institute of Control and Computation Engineering University of Zielona Gora, 65-417 Zielona Gora Poland.
Edyta Wawrzyniak-GramackaDepartment of Applied and Clinical Physiology, Collegium Medicum University of Zielona Gora, 65-417 Zielona Gora, Poland.
Anna TylutkaDepartment of Applied and Clinical Physiology, Collegium Medicum University of Zielona Gora, 65-417 Zielona Gora, Poland.
Natalia HertmanowskaDepartment of Applied and Clinical Physiology, Collegium Medicum University of Zielona Gora, 65-417 Zielona Gora, Poland.
Anna KasperskaDepartment of Physiology, University School of Physical Education in Poznan, 61-871 Poznan, Poland.
Miłosz CzubaDepartment of Applied and Clinical Physiology, Collegium Medicum University of Zielona Gora, 65-417 Zielona Gora, Poland.
University of Zielona Góra · PLInstytut Sportu · PLUniversity School of Physical Education in Kraków · PL

Funding

Narodowe Centrum Nauki [No NNZ705282University of Zielona Gora [No 222267/E-545/S/2019
6 · The paper itself

Abstract

Intermittent exposure to hypoxia (IHE) increases production of reactive oxygen and nitrogen species which, as signalling molecules, participate in tissue injury-repair-regeneration cascade. The process is also stimulated by arginine whose bioavailability is a limiting factor for NO synthesis. The effects of IHE in combination with arginine (Arg) intake on myogenesis and angiogenesis mediators were examined in a randomized and placebo-controlled trial. Blood samples were collected from 38 elite athletes on the 1st, 7th and 14th days during the training camp. The oral doses of arginine (2 × 6 g/day) and/or IHE using hypoxicator GO2Altitude (IHE and Arg/IHE) were applied. Serum NO and H

Indexed as

AltitudeArginineDouble-Blind MethodHumansHydrogen PeroxideHypoxiaIntercellular Signaling Peptides and ProteinsMaleNitric OxideOxygen ConsumptionRegenerationWrestlingArginineHydrogen PeroxideIntercellular Signaling Peptides and ProteinsNitric Oxideathletesgrowth factorshydrogen peroxidemuscle damagenitric oxide

Identifiers

PMID32610647
PMCPMC7400083
OpenAlexW3037639831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.