Evidence map›Paper›PMID 32610643›Full record

ArticleJournal of clinical medicine2020

Antimycobacterial Effects of Everolimus in a Human Granuloma Model.

David Ashley, Joshua Hernandez, Ruoqiong Cao, Kimberly To, Aram Yegiazaryan, Rachel Abrahem, Timothy Nguyen, James Owens, Maria Lambros, Selvakumar Subbian and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Recent advances in tuberculosis treatment: Towards shorter, safer, and more effective therapies.Journal of clinical tuberculosis and other mycobacterial diseases · 2026
    Review
  5. Review
  6. Review
  7. Host-directed therapy for tuberculosis.European journal of medical research · 2025
    Review
  8. Inducible antibacterial responses in macrophages.Nature reviews. Immunology · 2025
    Review
  9. Review
  10. The Role of mTOR inBiomedicines · 2024
    Review
  11. Review
  12. Review
  13. Pathogenicity of Type I Interferons inInternational journal of molecular sciences · 2023
    Review
  14. Evaluation of Everolimus Activity againstAntibiotics (Basel, Switzerland) · 2023
    Article
  15. Article
  16. Different modalities of host cell death and their impact onAmerican journal of physiology. Cell physiology · 2022
    Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

David AshleyGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA 91766, USA.
Joshua HernandezGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA 91766, USA.
Ruoqiong CaoCollege of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA 91766, USA.
Kimberly ToGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA 91766, USA.
Aram YegiazaryanGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA 91766, USA.
Rachel AbrahemGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA 91766, USA.
Timothy NguyenCollege of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA 91766, USA.
James OwensCollege of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA 91766, USA.
Maria LambrosCollege of Pharmacy, Western University of Health Sciences, Pomona, CA 91766, USA.
Selvakumar SubbianPublic Health Research Institute at the New Jersey Medical School, Rutgers-The State University of New Jersey, Newark, NJ 07103, USA.ORCID 0000-0003-2021-8632
Vishwanath VenketaramanGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA 91766, USA.ORCID 0000-0002-2586-1160
Western University of Health Sciences · USRutgers, The State University of New Jersey · US

Funding

Glutathione depletion in the CNS and its effects on Mtb infectionR15HL143545 · NHLBI · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI VENKETARAMAN, VISHWANATH · 2019 to 2024
$852k
NHLBI NIH HHS R15 HL143545NIH HHS RHL143545-01A1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AutophagyEverolimusHost-Directed therapymTORMycobacterium tuberculosis

Identifiers

PMID32610643
PMCPMC7409120
OpenAlexW3039942566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.