Evidence map›Paper›PMID 32610611›Full record

ReviewGenes2020

CDK Regulation of Meiosis: Lessons from

Anne M MacKenzie, Soni Lacefield

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Decoding Cdk1 control: from mitotic thresholds to meiotic specificity.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Meiotic Cytokinesis inJournal of fungi (Basel, Switzerland) · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Anne M MacKenzieDepartment of Biology, Indiana University, 1001 E. Third Street, Bloomington, IN 47405, USA.
Soni LacefieldDepartment of Biology, Indiana University, 1001 E. Third Street, Bloomington, IN 47405, USA.
Indiana University Bloomington · US

Funding

Timing and regulation of meiotic commitment in S cerevisiaeR01GM105755 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Soni Lacefield · 2014 to 2026
$4.1M
NIGMS NIH HHS R01 GM105755
6 · The paper itself

Abstract

Meiotic progression requires precise orchestration, such that one round of DNA replication is followed by two meiotic divisions. The order and timing of meiotic events is controlled through the modulation of the phosphorylation state of proteins. Key components of this phospho-regulatory system include cyclin-dependent kinase (CDK) and its cyclin regulatory subunits. Over the past two decades, studies in budding and fission yeast have greatly informed our understanding of the role of CDK in meiotic regulation. In this review, we provide an overview of how CDK controls meiotic events in both budding and fission yeast. We discuss mechanisms of CDK regulation through post-translational modifications and changes in the levels of cyclins. Finally, we highlight the similarities and differences in CDK regulation between the two yeast species. Since CDK and many meiotic regulators are highly conserved, the findings in budding and fission yeasts have revealed conserved mechanisms of meiotic regulation among eukaryotes.

Indexed as

MeiosisCyclin-Dependent KinasesCyclinsProtein Processing, Post-TranslationalSaccharomyces cerevisiae ProteinsSchizosaccharomyces pombe ProteinsYeastsCyclin-Dependent KinasesCyclinsSaccharomyces cerevisiae ProteinsSchizosaccharomyces pombe ProteinsAPC/Cbudding yeastCDKchromosome segregationcyclinCyclin-Dependent Kinasefission yeastmeiosis

Identifiers

PMID32610611
PMCPMC7397238
OpenAlexW3037581718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.