Evidence map›Paper›PMID 32610595›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Utilization of Multiparametric MRI of Prostate in Patients under Consideration for or Already in Active Surveillance: Correlation with Imaging Guided Target Biopsy.

Jinxing Yu, Ann S Fulcher, Sarah Winks, Mary A Turner, William Behl, Anna Lee Ware, Nitai D Mukhopadhyay, Candice Kim, Christopher Jackson, Harnek S Bajaj and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jinxing Yu¹Department of Radiology, Virginia Commonwealth University Health System, Main Hospital, 3rd Floor, 401 North 12th Street, Richmond, VA 23298, USA.
Ann S Fulcher¹Department of Radiology, Virginia Commonwealth University Health System, Main Hospital, 3rd Floor, 401 North 12th Street, Richmond, VA 23298, USA.
Sarah Winks¹Department of Radiology, Virginia Commonwealth University Health System, Main Hospital, 3rd Floor, 401 North 12th Street, Richmond, VA 23298, USA.
Mary A Turner¹Department of Radiology, Virginia Commonwealth University Health System, Main Hospital, 3rd Floor, 401 North 12th Street, Richmond, VA 23298, USA.
William Behl²School of Medicine, Virginia Commonwealth University Health System, Main Hospital, 401 North 12th Street, Richmond, VA 23298, USA.
Anna Lee WareDepartment of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24060, USA.
Nitai D MukhopadhyayDepartment of Biostatistics, Virginia Commonwealth University Health System, 401 North 12th Street, Richmond, VA 23298, USA.
Candice Kim²School of Medicine, Virginia Commonwealth University Health System, Main Hospital, 401 North 12th Street, Richmond, VA 23298, USA.
Christopher Jackson²School of Medicine, Virginia Commonwealth University Health System, Main Hospital, 401 North 12th Street, Richmond, VA 23298, USA.
Harnek S Bajaj²School of Medicine, Virginia Commonwealth University Health System, Main Hospital, 401 North 12th Street, Richmond, VA 23298, USA.
Lance J HamptonDepartment of Urology, Virginia Commonwealth University Health System, 401 North 12th Street, Richmond, VA 23298, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study sought to assess the value of multiparametric magnetic resonance image (mp-MRI) in patients with a prostate cancer (PCa) Gleason score of 6 or less under consideration for or already in active surveillance and to determine the rate of upgrading by target biopsy. Three hundred and fifty-four consecutive men with an initial transrectal ultrasound-guided (TRUS) biopsy-confirmed PCa Gleason score of 6 or less under clinical consideration for or already in active surveillance underwent mp-MRI and were retrospectively reviewed. One hundred and nineteen of 354 patients had cancer-suspicious regions (CSRs) at mp-MRI. Each CSR was assigned a Prostate Imaging Reporting and Data System (PI-RADS) score based on PI-RADS v2. One hundred and eight of 119 patients underwent confirmatory imaging-guided biopsy for CSRs. Pathology results including Gleason score (GS) and percentage of specimens positive for PCa were recorded. Associations between PI-RADS scores and findings at target biopsy were evaluated using logistic regression. At target biopsy, 81 of 108 patients had PCa (75%). Among them, 77 patients had upgrading (22%, 77 of 354 patients). One hundred and forty-six CSRs in 108 patients had PI-RADS 3

Indexed as

active surveillanceimaging-guided target prostate biopsymultiparametric MRIPI-RADS scoreprostate cancer

Identifiers

PMID32610595
PMCPMC7400343

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.