Evidence map›Paper›PMID 32610563›Full record

ArticleJournal of personalized medicine2020

Semantic Priming in Mild Cognitive Impairment and Healthy Subjects: Effect of Different Time of Presentation of Word-Pairs.

Valeria Guglielmi, Davide Quaranta, Ilaria Mega, Emanuele Maria Costantini, Claudia Carrarini, Alice Innocenti, Camillo Marra

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Valeria GuglielmiNeurology Unit, Fondazione Policlinico Agostino Gemelli-IRCCS, 00168 Rome, Italy.
Davide QuarantaNeurology Unit, Fondazione Policlinico Agostino Gemelli-IRCCS, 00168 Rome, Italy.
Ilaria MegaDepartment of Neuroscience, Catholic University of Sacred Heart, 00168 Rome, Italy.
Emanuele Maria CostantiniDepartment of Neuroscience, Catholic University of Sacred Heart, 00168 Rome, Italy.
Claudia CarrariniDepartment of Neuroscience, Catholic University of Sacred Heart, 00168 Rome, Italy.
Alice InnocentiDepartment of Neuroscience, Catholic University of Sacred Heart, 00168 Rome, Italy.
Camillo MarraDepartment of Neuroscience, Catholic University of Sacred Heart, 00168 Rome, Italy.

Funding

Linea D1 - Catholic University of Sacred heart R41245000307
6 · The paper itself

Abstract

introductionSemantic memory is impaired in mild cognitive impairment (MCI). Twomain hypotheses about this finding are debated and refer to the degradation of stored knowledgeversus the impairment of semantic access mechanisms. The aim of our study is to evaluate semanticimpairment in MCI versus healthy subjects (HS) by an experiment evaluating semantic priming.

methodsWe enrolled 27 MCI and 20 HS. MCI group were divided, according to follow up, intoconverters-MCI and non converters-MCI. The semantic task consisted of 108 pairs of words, 54 ofwhich were semantically associated. Stimuli were presented 250 or 900 ms later the appearance ofthe target in a randomized manner. Data were analyzed using factorial ANOVA.

resultsBoth HSand MCI answered more quickly for word than for non-word at both stimulus onset asynchrony(SOA) intervals. At 250 ms, both MCI and HS experienced a shorter time of response for relatedwordthan for unrelated words (priming effect), while only the converters-MCI subgroup lost thepriming effect. Further, we observed a rather larger Cohen's d effect size in non converters-MCIthan in converters-MCI.

conclusionOur data, and in particular the absence of a semantic primingeffect in converters-MCI, could reflect the impairment of semantic knowledge rather than theaccessibility of semantic stores in MCI individuals that progress to dementia.

Indexed as

Alzheimer diseasemild cognitive impairmentsemantic priming

Identifiers

PMID32610563
PMCPMC7564260

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