Evidence map›Paper›PMID 32610063›Full record

ArticleNeuroImage2020

An open database of resting-state fMRI in awake rats.

Yikang Liu, Pablo D Perez, Zilu Ma, Zhiwei Ma, David Dopfel, Samuel Cramer, Wenyu Tu, Nanyin Zhang

Open access · goldAbstract read
In one paragraph

Article in NeuroImage, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Where do we stand on fMRI in awake mice?Cerebral cortex (New York, N.Y. : 1991) · 2024
    Pooled it
  2. Article
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  8. Review
  9. Article
  10. Article
  11. The Role of Claustrum in Incubation of Opioid Seeking after Electric Barrier-Induced Voluntary Abstinence in Male and Female Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  12. Neuroimaging Model of Visceral Manipulation in an Awake Rat.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  13. Article
  14. Article
  15. High-resolution awake mouse fMRI at 14 Tesla.bioRxiv : the preprint server for biology · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Exploring memory-related network via dorsal hippocampus suppression.Network neuroscience (Cambridge, Mass.) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yikang LiuDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 16802, USA.
Pablo D PerezDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 16802, USA.
Zilu MaDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 16802, USA.
Zhiwei MaDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 16802, USA.
David DopfelDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 16802, USA.
Samuel CramerNeuroscience Program, The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, 16802, USA.
Wenyu TuNeuroscience Program, The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, 16802, USA.
Nanyin ZhangDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, PA, 16802, USA; Neuroscience Program, The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, 16802, USA. Electronic address: nuz2@psu.edu.
Pennsylvania State University · US

Funding

Mechanistic dissection of the neural basis of the resting-state fMRI signal using multi-modal approachesRF1MH114224 · NIMH · PENNSYLVANIA STATE UNIVERSITY, THE · PI DREW, PATRICK JAMES, ZHANG, NANYIN · 2017 to 2018
$3.8M
Resting-state Neural Networks in Awake RodentsR01NS085200 · NINDS · PENNSYLVANIA STATE UNIVERSITY, THE · PI ZHANG, NANYIN · 2013 to 2024
$3.4M
Longitudinal assessment of trauma on neural circuitry development into adulthoodR01MH098003 · NIMH · PENNSYLVANIA STATE UNIVERSITY, THE · PI KING, JEAN A, ZHANG, NANYIN · 2013 to 2017
$1.8M
NIMH NIH HHS R01 MH098003NIMH NIH HHS RF1 MH114224NINDS NIH HHS R01 NS085200
6 · The paper itself

Abstract

Rodent models are essential to translational research in health and disease. Investigation in rodent brain function and organization at the systems level using resting-state functional magnetic resonance imaging (rsfMRI) has become increasingly popular. Due to this rapid progress, publicly shared rodent rsfMRI databases can be of particular interest and importance to the scientific community, as inspired by human neuroscience and psychiatric research that are substantially facilitated by open human neuroimaging datasets. However, such databases in rats are still rare. In this paper, we share an open rsfMRI database acquired in 90 rats with a well-established awake imaging paradigm that avoids anesthesia interference. Both raw and preprocessed data are made publicly available. Procedures in data preprocessing to remove artefacts induced by the scanner, head motion and non-neural physiological noise are described in details. We also showcase inter-regional functional connectivity and functional networks obtained from the database.

Indexed as

Databases, FactualMagnetic Resonance ImagingAnimalsBrainBrain MappingDefault Mode NetworkFunctional NeuroimagingImage Processing, Computer-AssistedRatsAwakeDatabaseRatResting-state fMRI

Identifiers

PMID32610063
PMCPMC7605641
OpenAlexW3037722287

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.