ArticleEMBO molecular medicine2020
STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells.
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Article in EMBO molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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0cells of the map it votes in
30citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
What it found
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Who cites it
30 citing papers in PubMed, 56 citations in OpenAlex.
- Deletion of STIM1 in Treg cells protects against lung fibrosis and associated cardiovascular complications in a pre-clinical mouse model.Redox biology · 2026Article
- T cell cholesterol transport links intestinal immune responses to dietary lipid absorption.Science (New York, N.Y.) · 2025Article
- A novel variant in the STIM1 gene leading to combined immunodeficiency and congenital myopathy.Immunologic research · 2025Article
- Calcium Release-Activated Calcium Modulator ORAI1-Sensitive Serine Dehydratase Regulates Fatty Acid-Induced CD4Animals : an open access journal from MDPI · 2025Article
- From Skin and Gut to the Brain: The Infectious Journey of the Human Commensal Fungus Malassezia and Its Neurological Consequences.Molecular neurobiology · 2025Review
- Analysis of Store-Operated CaMethods in molecular biology (Clifton, N.J.) · 2025Article
- Polymorphism-driven immune disruptions in Kawasaki disease across populations: decoding the role of T and B-cells.Frontiers in immunology · 2025Review
- Discovery of selective Orai channel blockers bearing an indazole or a pyrazole scaffold.European journal of medicinal chemistry · 2024Article
- Rapamycin Controls Lymphoproliferation and Reverses T-Cell Responses in a Patient with a Novel STIM1 Loss-of-Function Deletion.Journal of clinical immunology · 2024Article
- Activating mutations in JAK2 and CALR differentially affect intracellular calcium flux in store operated calcium entry.Cell communication and signaling : CCS · 2024Article
- Multifaceted control of T cell differentiation by STIM1.Trends in biochemical sciences · 2023Review
- miRNA-132-5p mediates a negative feedback regulation of IL-8 secretion through S100A8/A9 downregulation in neutrophil-like HL-60 cells.Frontiers in immunology · 2023Article
- TWEAK-Fn14 Axis Induces Calcium-Associated Autophagy and Cell Death To Control Mycobacterial Survival in Macrophages.Microbiology spectrum · 2022Article
- Distinct roles of ORAI1 in T cell-mediated allergic airway inflammation and immunity to influenza A virus infection.Science advances · 2022Article
- Store-operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease.EMBO molecular medicine · 2022Article
- Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated CaNature communications · 2022Article
- CaJournal of immunology (Baltimore, Md. : 1950) · 2022Article
- The roles of fungus in CNS autoimmune and neurodegeneration disorders.Frontiers in immunology · 2022Review
- Targeting SOCE in Intestinal Epithelial Cells: A New Treatment Concept for Inflammatory Bowel Disease?Cellular and molecular gastroenterology and hepatology · 2022Article
- Metabolic requirements of Th17 cells and of B cells: Regulation and defects in health and in inflammatory diseases.Frontiers in immunology · 2022Review
Corrections and comments
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Authors and funding
20 authors at 5 institutions in 2 countries.
Sascha KahlfussDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0001-8813-1061
Ulrike KaufmannDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Axel R ConcepcionDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Lucile NoyerDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Dimitrius RaphaelDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Martin VaethDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Jun YangDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Priya PancholiDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Mate MausDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
James MullerDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Lina KozhayaThe Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Alireza Khodadadi-JamayranDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Zhengxi SunDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Patrick ShawDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.
Derya UnutmazThe Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Peter B StathopulosDepartment of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.ORCID 0000-0002-0536-6656
Cori FeistDepartment of Obstetrics & Gynecology, Oregon Health & Science University, Portland, OR, USA.
Scott B CameronDivision of Allergy and Clinical Immunology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Stuart E TurveyDivision of Allergy and Clinical Immunology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Stefan FeskeDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0001-5431-8178
New York University · USJackson Laboratory · USUniversity of British Columbia · CAOregon Health & Science University · USWestern University · CA
Funding
Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANIRBAN MAITRA · 1985 to 2026
$83.1MCRAC Channel Deficiency in Immunity to InfectionR01AI097302 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2012 to 2022
$5.6MImmunobiology of Regulatory T Cells in HIV InfectionR01AI065303 · NIAID · VANDERBILT UNIVERSITY · PI UNUTMAZ, DERYA · 2005 to 2015
$4.3MRegulation of Follicular T cell Responses in the Lung by Ion ChannelsR01AI130143 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2017 to 2021
$2.4MRegulation of encephalitogenic T cells by CRAC channelsR01AI137004 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2018 to 2022
$2.4MAcquisition of a Seahorse XFS10OD016304 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RAMASAMY, RAVICHANDRAN · 2013 to 2013
$126kDeutsche Forschungsgemeinschaft (DFG) KA 4083/2-1Deutsche Forschungsgemeinschaft (DFG) KA 4514/1-1Deutsche Forschungsgemeinschaft (DFG) VA 882/1-1HHS|NIH|National Cancer Institute (NCI) P30CA016087HHS|NIH|National Institute of Allergy and Infectious Diseases (NIAID) AI065303HHS|NIH|National Institute of Allergy and Infectious Diseases (NIAID) AI097302HHS|NIH|National Institute of Allergy and Infectious Diseases (NIAID) AI137004HHS|NIH|NIH Office of the Director (OD) S10OD016304-01National Multiple Sclerosis Society (National MS Society) FG-1608-25544NCI NIH HHS P30 CA016087NIAID NIH HHS R01 AI065303NIAID NIH HHS R01 AI097302NIAID NIH HHS R01 AI137004NIH HHS S10 OD016304
Abstract
Immunity to fungal infections is mediated by cells of the innate and adaptive immune system including Th17 cells. Ca
Indexed as
CalciumTh17 CellsAnimalsAntifungal AgentsCalcium ChannelsHumansMiceNeoplasm ProteinsORAI1 ProteinStromal Interaction Molecule 1Antifungal AgentsCalciumCalcium ChannelsNeoplasm ProteinsORAI1 ProteinSTIM1 protein, humanStim1 protein, mouseStromal Interaction Molecule 1Ca2+ channelCandida albicansimmunodeficiencySTIM1Th17 cells
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.