ArticleJournal of biophotonics2020
Raman spectroscopy-based detection of RNA viruses in saliva: A preliminary report.
Article in Journal of biophotonics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 54 citations in OpenAlex.
- Extraoral Detection of Biomarkers and Pathogens in Saliva: Comprehensive, Panoramic Review.Biosensors · 2026Review
- Development of a Raman-Based Method for the Diagnosis of People with Obstructive Sleep Apnea Syndrome: The Role of Lactic Acid.International journal of molecular sciences · 2025Article
- Article
- Raman Multi-Omic Snapshot and Statistical Validation of Structural Differences between Herpes Simplex Type I and Epstein-Barr Viruses.International journal of molecular sciences · 2023Article
- Optical Biosensors for the Diagnosis of COVID-19 and Other Viruses-A Review.Diagnostics (Basel, Switzerland) · 2023Review
- Raman spectroscopy for viral diagnostics.Biophysical reviews · 2023Review
- Current trends in COVID-19 diagnosis and its new variants in physiological fluids: Surface antigens, antibodies, nucleic acids, and RNA sequencing.Trends in analytical chemistry : TRAC · 2022Review
- Article
- Review
- A Machine Learning Framework for Detecting COVID-19 Infection Using Surface-Enhanced Raman Scattering.Biosensors · 2022Article
- Fluorescence spectrophotometry for COVID-19 determination in clinical swab samples.Arabian journal of chemistry · 2022Article
- Saliva as a propitious diagnostic biofluid, biomarker, and bodies first line of defense against COVID-19: A review.Journal of family medicine and primary care · 2022Review
- Diagnosing COVID-19 in human serum using Raman spectroscopy.Lasers in medical science · 2022Article
- Review
- Determination of the denaturation temperature of the Spike protein S1 of SARS-CoV-2 (2019 nCoV) by Raman spectroscopy.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2022Article
- Spectroscopy: a versatile sensing tool for cost-effective and rapid detection of novel coronavirus (COVID-19).Emergent materials · 2022Review
- Specific intracellular signature of SARS-CoV-2 infection using confocal Raman microscopy.Communications chemistry · 2022Article
- Detection of SARS-CoV-2 and its S and N proteins using surface enhanced Raman spectroscopy.RSC advances · 2021Article
- Detection of COVID-19 Virus on Surfaces Using Photonics: Challenges and Perspectives.Diagnostics (Basel, Switzerland) · 2021Review
- Photonics of human saliva: potential optical methods for the screening of abnormal health conditions and infections.Biophysical reviews · 2021Review
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several non-invasive Raman spectroscopy-based assays have been reported for rapid and sensitive detection of pathogens. We developed a novel statistical model for the detection of RNA viruses in saliva, based on an unbiased selection of a set of 65 Raman spectral features that mostly attribute to the RNA moieties, with a prediction accuracy of 91.6% (92.5% sensitivity and 88.8% specificity). Furthermore, to minimize variability and automate the downstream analysis of the Raman spectra, we developed a GUI-based analytical tool "RNA Virus Detector (RVD)." This conceptual framework to detect RNA viruses in saliva could form the basis for field application of Raman Spectroscopy in managing viral outbreaks, such as the ongoing COVID-19 pandemic. (http://www.actrec.gov.in/pi-webpages/AmitDutt/RVD/RVD.html).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.