ArticleBiopreservation and biobanking2020
Biochemically Tracked Variability of Blood Plasma Thawed-State Exposure Times in a Multisite Collection Study.
Article in Biopreservation and biobanking, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- An accessible, absorbance-based plate reader assay to assess cumulative exposure of blood plasma & serum to thawed conditions.Methods (San Diego, Calif.) · 2026Article
- Kinetically Tunable, Subzero-Active, Visual Time-Temperature Indicators Based on the Permanganate-Oxalate Reaction.Reaction chemistry & engineering · 2025Article
- The Permanganate-Oxalate Reaction as a Visual Time-Temperature Indicator: Reaction Systems for Use Above 0 °C.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2025Article
- Delta-S-Cys-Albumin as a Marker of Pediatric Biospecimen Integrity.Biopreservation and biobanking · 2024Article
- Oxidized LDL is stable in human serum under extended thawed-state conditions ranging from -20 °C to room temperature.Journal of mass spectrometry and advances in the clinical lab · 2023Article
- Effect of acupuncture on pain and substance P levels in middle-aged women with chronic neck pain.Frontiers in neurology · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
The integrity of blood plasma/serum (P/S) specimens can be impacted by preanalytical handling and storage conditions that result in thawed-state exposures (> -30°C). We recently reported a simple dilute-and-shoot, intact-protein liquid chromatography/mass spectrometry (LC/MS) assay called ΔS-Cys-Albumin that quantifies cumulative exposure of P/S to thawed conditions based on the change in relative abundance of the oxidized (S-cysteinylated) proteoform of albumin (S-Cys-Albumin) in the native sample to that of an aliquot of the sample intentionally driven to its maximum oxidation state. Herein, we evaluated the effect of prestorage delay and initial storage temperature on sample integrity by applying the ΔS-Cys-Albumin assay to a set of plasma samples (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.