Evidence map›Paper›PMID 32608977›Full record

ArticleJournal of the American Chemical Society2020

Hydrogen Bonding Phase-Transfer Catalysis with Ionic Reactants: Enantioselective Synthesis of γ-Fluoroamines.

Giulia Roagna, David M H Ascough, Francesco Ibba, Anna Chiara Vicini, Alberto Fontana, Kirsten E Christensen, Aldo Peschiulli, Daniel Oehlrich, Antonio Misale, Andrés A Trabanco and 3 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Asymmetric phase-transfer catalysis.Nature reviews. Chemistry · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Closing the gap betweenEJNMMI radiopharmacy and chemistry · 2021
    Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Giulia RoagnaUniversity of Oxford, Chemistry Research Laboratory, 12 Mansfield Road, Oxford OX1 3TA, U.K.
David M H AscoughUniversity of Oxford, Chemistry Research Laboratory, 12 Mansfield Road, Oxford OX1 3TA, U.K.
Francesco IbbaUniversity of Oxford, Chemistry Research Laboratory, 12 Mansfield Road, Oxford OX1 3TA, U.K.
Anna Chiara ViciniUniversity of Oxford, Chemistry Research Laboratory, 12 Mansfield Road, Oxford OX1 3TA, U.K.
Alberto FontanaDiscovery Chemistry, Janssen Research & Development, Janssen-Cilag S.A., Calle Jarama 75A, 45007 Toledo, Spain.
Kirsten E ChristensenUniversity of Oxford, Chemistry Research Laboratory, 12 Mansfield Road, Oxford OX1 3TA, U.K.
Aldo PeschiulliDiscovery Sciences Medicinal Chemistry, Janssen Research & Development, Janssen Pharmaceutica N.V., Turnhoutseweg 30, B-2340 Beerse, Belgium.
Daniel OehlrichDiscovery Sciences Medicinal Chemistry, Janssen Research & Development, Janssen Pharmaceutica N.V., Turnhoutseweg 30, B-2340 Beerse, Belgium.ORCID 0000-0002-3392-1952
Antonio MisaleDiscovery Chemistry, Janssen Research & Development, Janssen-Cilag S.A., Calle Jarama 75A, 45007 Toledo, Spain.
Andrés A TrabancoDiscovery Chemistry, Janssen Research & Development, Janssen-Cilag S.A., Calle Jarama 75A, 45007 Toledo, Spain.ORCID 0000-0002-4225-758X
Robert S PatonUniversity of Oxford, Chemistry Research Laboratory, 12 Mansfield Road, Oxford OX1 3TA, U.K.ORCID 0000-0002-0104-4166
Gabriele PupoUniversity of Oxford, Chemistry Research Laboratory, 12 Mansfield Road, Oxford OX1 3TA, U.K.ORCID 0000-0003-3084-3888
Véronique GouverneurUniversity of Oxford, Chemistry Research Laboratory, 12 Mansfield Road, Oxford OX1 3TA, U.K.ORCID 0000-0001-8638-5308

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ammonium salts are used as phase-transfer catalysts for fluorination with alkali metal fluorides. We now demonstrate that these organic salts, specifically azetidinium triflates, are suitable substrates for enantioselective ring opening with CsF and a chiral

Identifiers

PMID32608977
PMCPMC7441491

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.