Evidence map›Paper›PMID 32608543›Full record

ArticleTransplant infectious disease : an official journal of the Transplantation Society2020

T-cell adoptive immunotherapy for BK nephropathy in renal transplantation.

Sadia Jahan, Carla Scuderi, Leo Francis, Michelle A Neller, Sweera Rehan, Pauline Crooks, George R Ambalathingal, Corey Smith, Rajiv Khanna, George T John

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Transplant infectious disease : an official journal of the Transplantation Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Adoptive T-cell therapy for virus-associated diseases.Clinical microbiology reviews · 2025
    Review
  3. Review
  4. BK Polyomavirus-associated nephropathy - diagnostic and treatment standard.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Review
  5. Article
  6. Virus-Specific T-Cell Therapy for the Management of Viral Infections in the Immunocompromised.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2025
    Review
  7. Article
  8. BK viral infection: A review of management and treatment.World journal of transplantation · 2023
    Review
  9. Review
  10. Long-Term Infectious Complications of Kidney Transplantation.Clinical journal of the American Society of Nephrology : CJASN · 2022
    Review
  11. T-cell adoptive immunotherapy for BK nephropathy in renal transplantation.Transplant infectious disease : an official journal of the Transplantation Society · 2020
    Article
  12. Cellular Immunity Against BK Polyomavirus in Kidney Transplant Recipients: A Comprehensive Review.Transplant infectious disease : an official journal of the Transplantation Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sadia JahanKidney Health Service, Royal Brisbane and Women's Hospital, Herston, Qld, Australia.ORCID https://orcid.org/0000-0001-5557-4552
Carla ScuderiKidney Health Service, Royal Brisbane and Women's Hospital, Herston, Qld, Australia.
Leo FrancisPathology Department, Royal Brisbane and Women's Hospital, Herston, Qld, Australia.
Michelle A NellerQIMR Berghofer Centre for Immunotherapy and Vaccine Development, QIMR Berghofer Medical Research Institute, Herston, Qld, Australia.
Sweera RehanQIMR Berghofer Centre for Immunotherapy and Vaccine Development, QIMR Berghofer Medical Research Institute, Herston, Qld, Australia.
Pauline CrooksQIMR Berghofer Centre for Immunotherapy and Vaccine Development, QIMR Berghofer Medical Research Institute, Herston, Qld, Australia.
George R AmbalathingalQIMR Berghofer Centre for Immunotherapy and Vaccine Development, QIMR Berghofer Medical Research Institute, Herston, Qld, Australia.
Corey SmithQIMR Berghofer Centre for Immunotherapy and Vaccine Development, QIMR Berghofer Medical Research Institute, Herston, Qld, Australia.
Rajiv KhannaQIMR Berghofer Centre for Immunotherapy and Vaccine Development, QIMR Berghofer Medical Research Institute, Herston, Qld, Australia.
George T JohnKidney Health Service, Royal Brisbane and Women's Hospital, Herston, Qld, Australia.
QIMR Berghofer Medical Research Institute · AURoyal Brisbane and Women's Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBK virus (BKPyV) nephropathy occurs in 1%-10% of kidney transplant recipients, with suboptimal therapeutic options. CASE: A 54-year-old woman received a transplant in March 2017. BKPyV was detected at 1.5 × 10 DISCUSSION: We conclude that the T-cell adoptive immunotherapy reduced BKPyV load significantly despite extensive infection, but attendant fibrosis and tubular atrophy led to graft failure. Early intervention with T-cell therapy may prove efficacious in BKPyV nephropathy.

Indexed as

BK VirusImmunotherapy, AdoptiveKidney TransplantationPolyomavirus InfectionsTumor Virus InfectionsAustraliaFemaleHumansLeukocytes, MononuclearMiddle AgedT-LymphocytesBKPyV nephropathyBK virusT-cell adoptive immunotherapy

Identifiers

PMID32608543
PMCPMC7816252
OpenAlexW3039465484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.