ArticleOrganic & biomolecular chemistry2020
Picoloyl protecting group in synthesis: focus on a highly chemoselective catalytic removal.
Article in Organic & biomolecular chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Who cites it
6 citing papers in PubMed.
- Application of the Hydrogen-Bond-Mediated Aglycone Delivery (HAD) Reaction to the Synthesis of α- and β-Linked 2-Azido-2-deoxyglucosides.Chemistry, an Asian journal · 2026Article
- Article
- Cooperatively Catalyzed Activation of Thioglycosides with Iodine and Iron(III) Trifluoromethanesulfonate.Molecules (Basel, Switzerland) · 2025Article
- Recent Advances in Synthetic Strategies of Glycans and their Pharmaceutical Applications.Current medicinal chemistry · 2025Review
- Cooperatively Catalyzed Activation of Thioglycosides That Bypasses Intermediacy of Glycosyl Halides.Chemistry (Weinheim an der Bergstrasse, Germany) · 2023Article
- Broadening the Scope of the Reverse Orthogonal Strategy for Oligosaccharide Synthesis.The Journal of organic chemistry · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The picoloyl ester (Pico) has proven to be a versatile protecting group in carbohydrate chemistry. It can be used for the purpose of stereocontrolling glycosylations via an H-bond-mediated Aglycone Delivery (HAD) method. It can also be used as a temporary protecting group that can be efficiently introduced and chemoselectively cleaved in the presence of practically all other common protecting groups used in synthesis. Herein, we will describe a new method for rapid, catalytic, and highly chemoselective removal of the picoloyl group using inexpensive copper(ii) or iron(iii) salts.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.