ArticleJournal of molecular neuroscience : MN2021
Influence of Two Single-Nucleotide Polymorphisms of the Oxytocin Receptor Gene (OXTR) on Empathy: the Mediation Role of a Primary Emotion, CARE.
Article in Journal of molecular neuroscience : MN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Molecular genetic basis of the primary emotions in young adults: an exploratory analysis of genetic polymorphisms across dopamine, serotonin, oxytocin, endogenous opioid, and neurotrophic factor pathways.Frontiers in pharmacology · 2025Article
- Roles of the Oxytocin Receptor (OXTR) in Human Diseases.International journal of molecular sciences · 2023Review
- Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
To feel other's pain would elicit empathy. Some theorists hypothesized that observing other's pain may activate the primary emotion of maternal care instinct, which may function as a precursor of empathy. The maternal care instinct and empathy share the same genetic background and neuroendocrine underpinnings. An extensive body of research has shown that maternal behaviors relate to the oxytocinergic system, which has a strong influence on empathy. These studies suggest that the maternal care instinct may mediate the effect of oxytocin receptor gene (OXTR) on empathy. To provide evidence for this mediation, we used the subscale of CARE in Affective Neuroscience Personality Scales (ANPS) to measure the maternal care instinct and tested two OXTR single-nucleotide polymorphisms (SNPs), rs53576 and rs13316193, in 880 high school participants (588 females, 292 males; M
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