Evidence map›Paper›PMID 32607739›Full record

ArticleNeuroscience bulletin2020

Prevalence of Autism Spectrum Disorder in China: A Nationwide Multi-center Population-based Study Among Children Aged 6 to 12 Years.

Hao Zhou, Xiu Xu, Weili Yan, Xiaobing Zou, Lijie Wu, Xuerong Luo, Tingyu Li, Yi Huang, Hongyan Guan, Xiang Chen and 18 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroscience bulletin, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05531669 (Effect of PLAY Project Intervention Program on Children With Autism Spectrum Disorder), which is not on this map. Cited by 231 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
231citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05531669 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Effect of PLAY Project Intervention Program on Children With Autism Spectrum Disorder: A Multi-center, Randomized Control Study in China

TypeinterventionalSponsorTongji HospitalRan2022 to 2023Enrolled200ConditionsAutism Spectrum DisorderArmsPLAY Project, Parental Education
3 · Its place in the literature

Who cites it

231 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  6. Global prevalence of autism: A systematic review update.Autism research : official journal of the International Society for Autism Research · 2022
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  18. Elevation of HNeuroscience bulletin · 2026
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171 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

28 authors.

Hao ZhouDepartment of Neurology, Children's Hospital of Fudan University, Shanghai, 201102, China.ORCID http://orcid.org/0000-0002-7269-545X
Xiu XuChild Health Care, Children's Hospital of Fudan University, Shanghai, 201102, China.
Weili YanDepartment of Clinical Epidemiology, Children's Hospital of Fudan University, Shanghai, 201102, China.
Xiaobing ZouChild Development Behavior Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, China.
Lijie WuDepartment of Children and Adolescent Health, School of Public Health, Harbin Medical University, Harbin, 150081, China.
Xuerong LuoDepartment of Psychiatry, The Second Xiangya Hospital of Central South University, Changsha, 410011, China.
Tingyu LiChild Health Care, Children's Hospital of Chongqing Medical University, Chongqing, 400014, China.
Yi HuangDepartment of Psychiatry, West China Hospital of Sichuan University, Chengdu, 610041, China.
Hongyan GuanCapital Institute of Pediatrics, Beijing, 100020, China.
Xiang ChenThe Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325027, China.
Meng MaoChild Health Care, Chengdu Women and Children's Hospital, Chengdu, 610091, China.
Kun XiaCenter for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410013, China.
Lan ZhangChild Health Care, Chengdu Women and Children's Hospital, Chengdu, 610091, China.
Erzhen LiCapital Institute of Pediatrics, Beijing, 100020, China.
Xiaoling GeChildren's Hospital of Fudan University, Shanghai, 201102, China.
Lili ZhangDepartment of Neurology, Children's Hospital of Fudan University, Shanghai, 201102, China.
Chunpei LiDepartment of Neurology, Children's Hospital of Fudan University, Shanghai, 201102, China.
Xudong ZhangChildren's Hospital of Fudan University, Shanghai, 201102, China.
Yuanfeng ZhouDepartment of Neurology, Children's Hospital of Fudan University, Shanghai, 201102, China.
Ding DingHuashan Hospital of Fudan University, Shanghai, 200040, China.
Andy ShihAutism Speaks, 1 East 33rd Street, New York, NY, 10016, USA.
Eric FombonneOregon Health and Science University, Portland, OR, 97239, USA.
Yi ZhengBeijing Anding Hospital, Capital Medical University, Beijing, 100088, China.
Jisheng HanNeuroscience Research Institute, Peking University, Beijing, 100191, China.
Zhongsheng SunBeijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, 100021, China.
Yong-Hui JiangDepartment of Genetics and Pediatrics, Yale School of Medicine, New Haven, CT, 06520, USA.
Yi WangDepartment of Neurology, Children's Hospital of Fudan University, Shanghai, 201102, China. yiwang@shmu.edu.cn.
LATENT-NHC Study Team

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

This study aimed to obtain the first national estimate of the prevalence of autism spectrum disorder (ASD) in Chinese children. We targeted the population of 6 to 12-year-old children for this prevalence study by multistage convenient cluster sampling. The Modified Chinese Autism Spectrum Rating Scale was used for the screening process. Of the target population of 142,086 children, 88.5% (n = 125,806) participated in the study. A total of 363 children were confirmed as having ASD. The observed ASD prevalence rate was 0.29% (95% CI: 0.26%-0.32%) for the overall population. After adjustment for response rates, the estimated number of ASD cases was 867 in the target population sample, thereby achieving an estimated prevalence of 0.70% (95% CI: 0.64%-0.74%). The prevalence was significantly higher in boys than in girls (0.95%; 95% CI: 0.87%-1.02% versus 0.30%; 95% CI: 0.26%-0.34%; P < 0.001). Of the 363 confirmed ASD cases, 43.3% were newly diagnosed, and most of those (90.4%) were attending regular schools, and 68.8% of the children with ASD had at least one neuropsychiatric comorbidity. Our findings provide reliable data on the estimated ASD prevalence and comorbidities in Chinese children.

Indexed as

Autism Spectrum DisorderChildChinaComorbidityCross-Sectional StudiesFemaleHumansMalePrevalenceAutism spectrum disorderAutism Spectrum Rating ScaleChinaCo-morbidityPrevalence

Identifiers

PMID32607739
PMCPMC7475160

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.