Evidence map›Paper›PMID 32607731›Full record

ArticleJournal of neuro-oncology2020

Hypofractionated stereotactic radiosurgery for large-sized skull base meningiomas.

Hyuk-Jin Oh, Young Hyun Cho, Jeong Hoon Kim, Chang Jin Kim, Do Hoon Kwon, Doheui Lee, KyoungJun Yoon

Abstract read
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In one paragraph

Article in Journal of neuro-oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
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  4. Review
  5. Article
  6. Review
  7. Article
  8. Treatment Strategies and Current Results of Petroclival Meningiomas.Advances and technical standards in neurosurgery · 2023
    Article
  9. Article
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hyuk-Jin OhDepartment of Neurosurgery, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
Young Hyun ChoDepartment of Neurosurgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. yhyunc@amc.seoul.kr.ORCID http://orcid.org/0000-0002-3274-5096
Jeong Hoon KimDepartment of Neurosurgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Chang Jin KimDepartment of Neurosurgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Do Hoon KwonDepartment of Neurosurgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Doheui LeeRadiosurgery Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
KyoungJun YoonRadiosurgery Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Ulsan College · KRSoonchunhyang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAlthough stereotactic radiosurgery (SRS) has been proven to be effective and safe for treating intracranial meningiomas, concerns have been raised about the use of SRS for large-sized tumors involving the skull base that frequently encroach onto adjacent critical neural structures. The purpose of this study was to investigate the role of hypofractionated SRS as a therapeutic option for large-sized skull base meningiomas.

methodsThirty-one consecutive patients (median age: 55 years, 9 men and 22 women) who had been treated with hypofractionated SRS using CyberKnife for large-sized skull base meningiomas (> 10 cm

resultsWith a median follow-up of 57 months (range 9-98 months), tumor control was achieved for 28 (90.3%) of 31 patients. Treatment response on MRI included partial response (volume decrease > 20%) in 17 (54.8%) patients, stable in 11 (35.5%), and progression (volume increase > 20%) in 3 (9.7%). Of 21 patients with cranial neuropathy, 20 (95.2%) showed improved neurological status.

conclusionsOur current results suggest a promising role of hypofractionated SRS for large-sized skull base megningiomas in terms of tumor control and neurological outcomes. It is a reasonable therapeutic option for select patients.

Indexed as

AdultAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMeningeal NeoplasmsMeningiomaMiddle AgedPrognosisRadiation Dose HypofractionationRadiosurgeryRetrospective StudiesSkull Base NeoplasmsSurvival RateBrain neoplasmMeningiomaRadiosurgerySkull base

Identifiers

PMID32607731
OpenAlexW3039287104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.