Evidence map›Paper›PMID 32607503›Full record

ArticleF&S reports2020

Factors influencing postmortem disposition of cryopreserved sperm in men undergoing fertility preservation.

Ruben Blachman-Braun, Jordan C Best, W Austin Wyant, Libert Ramos, Emad Ibrahim, Ranjith Ramasamy

Open access · goldAbstract read
In one paragraph

Article in F&S reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ruben Blachman-BraunDepartment of Urology, University of Miami, Miller School of Medicine, Miami, Florida, USA.
Jordan C BestDepartment of Urology, University of Miami, Miller School of Medicine, Miami, Florida, USA.
W Austin WyantDepartment of Urology, University of Miami, Miller School of Medicine, Miami, Florida, USA.
Libert RamosDepartment of Urology, University of Miami, Miller School of Medicine, Miami, Florida, USA.
Emad IbrahimDepartment of Urology, University of Miami, Miller School of Medicine, Miami, Florida, USA.
Ranjith RamasamyDepartment of Urology, University of Miami, Miller School of Medicine, Miami, Florida, USA.
University of Miami · US

Funding

Miami Clinical and Translational Science InstituteUL1TR002736 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRASQUILLO, OLVEEN, KOBETZ, ERIN N · 2018 to 2022
$23.2M
NCATS NIH HHS UL1 TR002736
6 · The paper itself

Abstract

objectiveTo study the factors that influence men's disposition towards post-mortem disposition of their cryopreserved gametes.

designA retrospective chart review of sperm cryopreservations between June 2016 and January 2020 was performed. All patients ≥ 18 years of age were included. Samples intended for donation or records with an unspecified reason for preservation were excluded.

settingA large academic health center. PATIENTS: Participants' (n=217) mean age was 35.8 ± 10.8 years.

interventionsNot applicable.

main outcome measuresPatients' reason for undergoing sperm cryopreservation, method of retrieval, and whether they chose to have the sample preserved or discarded post-mortem.

resultsA total of 217 men were analyzed; mean age was 35.8 ± 10.8 years. Of those, 176 (81.1%) men decided to preserve their sperm for a spouse and 41 (18.9%) elected to have the sample discarded when choosing the fate of their cryopreserved sample should they die. There was no significant difference in disposition towards sample fate based on age or method of collection. However, there was a significant difference based on the "reason for cryopreservation" (p = 0.001). We found that compared to patients that underwent sperm cryopreservation due to cancer-related treatments, the patients that underwent sperm banking prior to vasectomy were more inclined to discard the sample (OR = 3.45, 95% CI: 1.16 - 10.27, p = 0.026). Men that collected the sperm as an in vitro fertilization backup were less willing to discard the sample (OR = 0.42, 95% CI: 0.18 - 0.97, p = 0.043).

conclusionsIt appears that men's disposition towards post-mortem disposition of their cryopreserved sperm are influenced by their reason for cryopreservation, rather than their age or method used for collection. As cryopreservation has become more common and affordable, understanding the factors that impact men's disposition towards the post-mortem disposition of the cryopreserved gametes is imperative, as this knowledge has the potential to influence institutional policies and legislation, and may help solve future legal conflicts and ethical dilemmas.

Indexed as

advanced directivescryopreservationsperm

Identifiers

PMID32607503
PMCPMC7326375
OpenAlexW3019793380

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.