Evidence map›Paper›PMID 32607499›Full record

ReviewResearch (Washington, D.C.)2020

Combating the Coronavirus Pandemic: Early Detection, Medical Treatment, and a Concerted Effort by the Global Community.

Zichao Luo, Melgious Jin Yan Ang, Siew Yin Chan, Zhigao Yi, Yi Yiing Goh, Shuangqian Yan, Jun Tao, Kai Liu, Xiaosong Li, Hongjie Zhang and 2 more

Abstract readReview
In one paragraph

Review in Research (Washington, D.C.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Diagnosis for COVID-19: current status and future prospects.Expert review of molecular diagnostics · 2021
    Review
  13. Review
  14. A Rapid SARS-CoV-2 RT-PCR Assay for Low Resource Settings.Diagnostics (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zichao LuoDepartment of Chemistry, National University of Singapore, Singapore 117543, Singapore.
Melgious Jin Yan AngDepartment of Chemistry, National University of Singapore, Singapore 117543, Singapore.
Siew Yin ChanFrontiers Science Center for Flexible Electronics & Shaanxi Institute of Flexible Electronics, Northwestern Polytechnical University, Xi'an 710072, China.
Zhigao YiDepartment of Chemistry, National University of Singapore, Singapore 117543, Singapore.
Yi Yiing GohDepartment of Chemistry, National University of Singapore, Singapore 117543, Singapore.
Shuangqian YanDepartment of Chemistry, National University of Singapore, Singapore 117543, Singapore.
Jun TaoSports Medical Centre, The Second Affiliated Hospital of Nanchang University, Nanchang 330000, China.
Kai LiuState Key Laboratory of Rare Earth Resource Utilization, Chang Chun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Xiaosong LiDepartment of Oncology, The Fourth Medical Center of Chinese People's Liberation Army General Hospital, Beijing 100048, China.
Hongjie ZhangState Key Laboratory of Rare Earth Resource Utilization, Chang Chun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.ORCID https://orcid.org/0000-0001-5433-8611
Wei HuangFrontiers Science Center for Flexible Electronics & Shaanxi Institute of Flexible Electronics, Northwestern Polytechnical University, Xi'an 710072, China.ORCID https://orcid.org/0000-0001-7004-6408
Xiaogang LiuDepartment of Chemistry, National University of Singapore, Singapore 117543, Singapore.ORCID https://orcid.org/0000-0003-2517-5790

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The World Health Organization (WHO) has declared the outbreak of 2019 novel coronavirus, known as 2019-nCoV, a pandemic, as the coronavirus has now infected over 2.6 million people globally and caused more than 185,000 fatalities as of April 23, 2020. Coronavirus disease 2019 (COVID-19) causes a respiratory illness with symptoms such as dry cough, fever, sudden loss of smell, and, in more severe cases, difficulty breathing. To date, there is no specific vaccine or treatment proven effective against this viral disease. Early and accurate diagnosis of COVID-19 is thus critical to curbing its spread and improving health outcomes. Reverse transcription-polymerase chain reaction (RT-PCR) is commonly used to detect the presence of COVID-19. Other techniques, such as recombinase polymerase amplification (RPA), loop-mediated isothermal amplification (LAMP), clustered regularly interspaced short palindromic repeats (CRISPR), and microfluidics, have allowed better disease diagnosis. Here, as part of the effort to expand screening capacity, we review advances and challenges in the rapid detection of COVID-19 by targeting nucleic acids, antigens, or antibodies. We also summarize potential treatments and vaccines against COVID-19 and discuss ongoing clinical trials of interventions to reduce viral progression.

Identifiers

PMID32607499
PMCPMC7315394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.