Evidence map›Paper›PMID 32607088›Full record

ArticleThe Yale journal of biology and medicine2020

Resolution of Recurrent Oro-facial Herpes Simplex Using a Topical Botanical Gel: A Case Report.

Erik O Nelson, Guillermo G Ruiz, Adam F Kozin, Tiffany C Turner, Edith V Langland, Jeffrey O Langland

Open access · greenAbstract readCase Reports
In one paragraph

Article in The Yale journal of biology and medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. The Power of Licorice (Healthcare (Basel, Switzerland) · 2023
    Review
  2. Viruses · 2023
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Erik O NelsonSouthwest College of Naturopathic Medicine, The Ric Scalzo Institute for Botanical Research, Tempe, AZ.
Guillermo G RuizSouthwest College of Naturopathic Medicine, The Ric Scalzo Institute for Botanical Research, Tempe, AZ.
Adam F KozinSouthwest College of Naturopathic Medicine, The Ric Scalzo Institute for Botanical Research, Tempe, AZ.
Tiffany C TurnerSouthwest College of Naturopathic Medicine, The Ric Scalzo Institute for Botanical Research, Tempe, AZ.
Edith V LanglandArizona State University, Biodesign Institute, Tempe, AZ.
Jeffrey O LanglandSouthwest College of Naturopathic Medicine, The Ric Scalzo Institute for Botanical Research, Tempe, AZ.
Arizona State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral herpes labialis, more commonly known as cold sores, are a common encountered viral infection involving herpes simplex virus-1 (HSV-1). Although relatively benign, these lesions can be both unsightly and clinically difficult to manage. Prescription standards of care and over-the-counter agents, such as docosonal, have often shown only limited efficacy in both decreasing lesional pain and reducing duration of lesional symptomology and are not without potential side effects. Despite some success with acute remediation, recurrent episodes often occur, with seemingly no imparted protection or suppression against future outbreaks. This case report involves the successful treatment of oro-facial herpes labialis with a synergistic botanical blend with marked reduction in symptoms, pain score, and lesion duration. Monitoring and evaluation post-treatment and application during future prodromal symptoms was also performed demonstrating additional reduction in the frequency of subsequent outbreaks. This case report supports the use of this treatment for prodromal and acute treatment of oro-facial herpes infection and appears to impart a reduction in the frequency of future outbreaks.

Indexed as

EleutherococcusGlycyrrhizaHerpes LabialisHypericumLavandulaMelissaSarraceniaceaeAdultAnalgesicsAnti-Inflammatory AgentsAntiviral AgentsDrug CompoundingFemaleGelsHumansSecondary PreventionAnalgesicsAnti-Inflammatory AgentsAntiviral AgentsGelsalternativebotanicalcold soreHerpes labialisHSV

Identifiers

PMID32607088
PMCPMC7309665
OpenAlexW3039932926

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.