Evidence map›Paper›PMID 32607034›Full record

ArticleNature and science of sleep2020

Does Nasal Obstruction Induce Obstructive Sleep Apnea in Healthy Women?

Islay Pittaway, Anna Ishkova, Helena Bean, Stephanie McCarthy, Isabella Lay, Joanne Avraam, Andrew Dawson, Therese Thornton, Christian L Nicholas, John Trinder and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature and science of sleep, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Islay PittawayMelbourne School of Psychological Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Anna IshkovaMelbourne School of Psychological Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Helena BeanMelbourne School of Psychological Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Stephanie McCarthyMelbourne School of Psychological Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Isabella LayMelbourne School of Psychological Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Joanne AvraamMelbourne School of Psychological Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Andrew DawsonMelbourne School of Psychological Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Therese ThorntonMelbourne School of Psychological Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0002-7742-1503
Christian L NicholasMelbourne School of Psychological Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
John TrinderMelbourne School of Psychological Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Fergal J O'DonoghueInstitute for Breathing and Sleep, Austin Health, Heidelberg, VIC 3084, Australia.
Melinda L JacksonInstitute for Breathing and Sleep, Austin Health, Heidelberg, VIC 3084, Australia.ORCID 0000-0003-4976-8101
Amy S JordanMelbourne School of Psychological Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0001-8561-9766
The University of Melbourne · AUInstitute for Breathing and Sleep · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeObstructive sleep apnea (OSA) is less prevalent among women and is associated with different symptoms and consequences to OSA in men. The reasons for these differences are unknown and difficult to tease apart in clinical populations. If OSA could be temporarily induced in healthy men and women, the causes of some of these differences could be investigated. Nasal blocking has been used to induce OSA in healthy men but its effect in women has not been reported. PATIENTS AND

methodsA total of 14 healthy individuals (10 women) underwent in-laboratory diagnostic sleep studies on two occasions separated by a week. On one occasion, the nasal passages were blocked, whereas on the other occasion, participants slept naturally. In both conditions, a full-face mask was used to monitor respiratory events. Participants' self-reported sleepiness, mood and performance on a motor learning task were assessed in the evening and morning of both sleep studies. Furthermore, endothelial function and self-reported sleep quality were assessed in the morning following each study.

resultsNasal blockage induced OSA in healthy young (age=22±3 years) and slim (BMI=22.2±3.2 kg/m

conclusionNasal blockage induces OSA in healthy, young, and normal weight women. However, whether the induced OSA is representative of naturally occurring OSA and the technique useful for future studies is unclear.

Indexed as

breathing routefemalenasal blockageobstructive sleep apneapathophysiologysexupper airway collapse

Identifiers

PMID32607034
PMCPMC7319502
OpenAlexW3036953250

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.