Evidence map›Paper›PMID 32606982›Full record

ArticleClinical epidemiology2020

Impact of Being Eligible for Type 2 Diabetes Treatment on All-Cause Mortality and Cardiovascular Events: Regression Discontinuity Design Study.

Irene Petersen, Sia Kromann Nicolaisen, Federico Ricciardi, Manuj Sharma, Reimar W Thomsen, Gianluca Baio, Lars Pedersen

Abstract read
In one paragraph

Article in Clinical epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Association between trabecular bone score and cardiovascular outcomes: a population-level historical cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  4. Article
  5. FRAX predicts cardiovascular risk in women undergoing osteoporosis screening: the Manitoba bone mineral density registry.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Irene PetersenDepartment of Primary Care and Population Health, University College London, London, UK.ORCID 0000-0002-0037-7524
Sia Kromann NicolaisenDepartment of Clinical Epidemiology, Aarhus University, Aarhus, Denmark.
Federico RicciardiDepartment of Statistical Science, University College London, London, UK.ORCID 0000-0002-4473-7691
Manuj SharmaDepartment of Primary Care and Population Health, University College London, London, UK.ORCID 0000-0002-6235-9866
Reimar W ThomsenDepartment of Clinical Epidemiology, Aarhus University, Aarhus, Denmark.ORCID 0000-0001-9135-3474
Gianluca BaioDepartment of Statistical Science, University College London, London, UK.ORCID 0000-0003-4314-2570
Lars PedersenDepartment of Clinical Epidemiology, Aarhus University, Aarhus, Denmark.

Funding

Medical Research Council MR/K014838/1
6 · The paper itself

Abstract

backgroundIndividuals with type 2 diabetes (T2D) have a twofold increased risk for cardiovascular events (CVE), and CVE is responsible for nearly 80% of the mortality. Current treatment guidelines state that individuals should immediately initiate antidiabetic treatment and cardiovascular risk-factor management from T2D diagnosis. However, the evidence base is sparse, and randomized trials are unlikely to be conducted. We examined the impact of being eligible for T2D treatment, as determined by the threshold of HbA METHODS AND

findingsWe used the regression discontinuity design (RDD), a quasi-experimental design, comparing rates of all-cause mortality and CVE in people just below and just above the eligibility for treatment threshold. We included Danish healthcare records from 43,070 individuals aged 40-80 years with no previous T2D record and the first record of HbA

conclusionIndividuals with first record of HbA

Indexed as

cardiovascular eventglycated hemoglobin A1cmortalityregression discontinuity designtype 2 diabetes

Identifiers

PMID32606982
PMCPMC7294562

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.