ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2020
Metabolic Score for Insulin Resistance Is Correlated to Adipokine Disorder and Inflammatory Activity in Female Knee Osteoarthritis Patients in a Chinese Population.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 29 citations in OpenAlex.
- Association of metabolic score for insulin resistance and preeclampsia: a multicenter cohort study.Lipids in health and disease · 2025Article
- Interaction of triglyceride glucose index and weight-adjusted waist circumference index in the risk of diabetes: from a national cohort study.BMC endocrine disorders · 2025Article
- Resistin upregulates fatty acid oxidation in synoviocytes of metabolic syndrome-associated knee osteoarthritis via CAP1/PKA/CREB to promote inflammation and catabolism.Arthritis research & therapy · 2025Article
- Association of metabolic score for insulin resistance with gestational diabetes mellitus: a multicenter cohort study.Frontiers in nutrition · 2025Article
- Association between obesity measurement indexes and symptomatic knee osteoarthritis among the Chinese population: analysis from a nationwide longitudinal study.BMC musculoskeletal disorders · 2024Observational
- Association between different insulin resistance surrogates and osteoarthritis: a cross-sectional study from NHANES 1999-2018.BMC musculoskeletal disorders · 2024Article
- Negative correlation between metabolic score for insulin resistance index and testosterone in male adults.Diabetology & metabolic syndrome · 2024Article
- Article
- Association between metabolic score for insulin resistance and cardiovascular disease mortality in patients with rheumatoid arthritis: evidence from the NHANES 1999-2018.Frontiers in endocrinology · 2024Article
- Magnitude and time course of insulin resistance accumulation with the risk of cardiovascular disease: an 11-years cohort study.Cardiovascular diabetology · 2023Article
- A Novel Metabolic Score for Insulin Resistance and Symptomatic Intracranial Hemorrhage in Ischemic Stroke Patients After Endovascular Thrombectomy.Neuropsychiatric disease and treatment · 2023Article
- Relationship between a novel non-insulin-based metabolic score for insulin resistance (METS-IR) and coronary artery calcification.BMC endocrine disorders · 2022Article
- Relationship of the metabolic score for insulin resistance and the risk of stroke in patients with hypertension: A cohort study.Frontiers in endocrinology · 2022Article
- The Nonlinear Correlation Between a Novel Metabolic Score for Insulin Resistance and Subclinical Myocardial Injury in the General Population.Frontiers in endocrinology · 2022Article
- Association Between a Novel Metabolic Score for Insulin Resistance and Mortality in People With Diabetes.Frontiers in cardiovascular medicine · 2022Article
- Article
- Val109Asp Polymorphism of the Omentin-1 Gene and Incidence of Knee Osteoarthritis in a Chinese Han Population: A Correlation Analysis.Drug design, development and therapy · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study was to evaluate the metabolic score for insulin resistance (METS-IR) in female knee osteoarthritis (KOA) patients in a Chinese population. The associations between METS-IR and adipokines, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) were investigated. PATIENTS AND
methodsThis study included 4686 women from the 2011 China Health and Retirement Longitudinal Study (CHARLS) and 108 women who underwent arthroplasty of KOA at a university hospital. The clinical data were collected, and adipokines were evaluated. METS-IR was calculated in the KOA patients and compared with the national baseline. Logistic regression analyses were applied to explore the associations of METS-IR with adipokines, ESR, and CRP.
resultsReceiver operating characteristic curve analysis of METS-IR and metabolic syndrome (MetS) in national baseline showed an area under the curve value of 0.851, with sensitivity of 0.777 and specificity of 0.772. The METS-IR of KOA was higher than the national baseline level (40.29 ± 6.98 vs 36.20 ± 8.50,
conclusionMETS-IR in female KOA was higher than that of the national baseline. The METS-IR was related to adipokine disorder and inflammatory activity. These findings suggest that METS-IR can be used to evaluate the degree of involvement of MetS in KOA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.