ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2020
The Predictive Ability of Two Triglyceride-Associated Indices for Gestational Diabetes Mellitus and Large for Gestational Age Infant Among Chinese Pregnancies: A Preliminary Cohort Study.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 4 of them syntheses that pooled it.
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Who cites it
47 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Association of triglyceride-glucose index and triglyceride-to-HDL cholesterol ratio with pregnancy-related risks: a meta-analysis.BMC pregnancy and childbirth · 2026Pooled it
- The correlation between triglyceride-glucose index in early pregnancy (<20 weeks) and pregnancy complications and adverse pregnancy outcomes: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Maternal metabolic factors and the association with gestational diabetes: A systematic review and meta-analysis.Diabetes/metabolism research and reviews · 2022Pooled it
- Gestational diabetes mellitus and adverse pregnancy outcomes: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2022 · on this mapPooled it
- Trial
- Second trimester serum lipidomics predicts large-for-gestational-age infants in apparently metabolically healthy pregnancies.iScience · 2026Article
- Restricted cubic spline analysis of the association between the third-trimester triglyceride-glucose index and neonatal birthweight in pregnant women with gestational diabetes mellitus: a multicenter cohort study.BMC pregnancy and childbirth · 2026Article
- Predictive value of six first-trimester insulin resistance indices for gestational diabetes mellitus and oral glucose tolerance test results.Diabetology & metabolic syndrome · 2026Article
- Relationship between lipid profiles and glycemic control in gestational diabetes mellitus women.BMC pregnancy and childbirth · 2026Article
- Metabolic biomarkers in early detection of gestational diabetes mellitus: a prospective diagnostic accuracy study.Frontiers in medicine · 2026Article
- Early Pregnancy Triglyceride to HDL-C Ratio Predicts Gestational Diabetes Mellitus and Neonatal Hypoglycemia: A Retrospective Cohort Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Predictive Value of the second-Trimester Triglyceride-Glucose Index and Its Derived Indices for Macrosomia in Gestational Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Liver as a metabolic sensor in gestational diabetes: Implications for offspring's liver and diabetes risk.World journal of hepatology · 2025Review
- Diagnostic Performance of the Triglyceride-Glucose Index in Screening for Gestational Diabetes Mellitus at 24-28 Weeks of Gestation.Diagnostics (Basel, Switzerland) · 2025Article
- Associations between triglyceride-glucose index in the early trimester of pregnancy and adverse pregnancy outcomes.BMC pregnancy and childbirth · 2025Article
- Assessment of first-trimester insulin resistance indices for gestational diabetes mellitus: a prospective cohort study.Journal of endocrinological investigation · 2025Article
- Predictive ability of lipid indices for large-for-gestational-age infants in pregnant females with gestational diabetes mellitus.World journal of diabetes · 2025Article
- Association Between Triglyceride-glucose Index, Its Trajectories and the Risk of Large for Gestational Age - Beijing Municipality, China, 2018-2022.China CDC weekly · 2025Article
- The first-trimester triglyceride glucose-body mass index is a valuable predictor for adverse pregnancy outcomes.BMC pregnancy and childbirth · 2025Article
- Pre-pregnancy BMI modifies the associations between triglyceride-glucose index in early pregnancy and adverse perinatal outcomes: a 5-year cohort study of 67,936 women in China.Diabetology & metabolic syndrome · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsTo investigate the potential of maternal first-trimester triglyceride (TG) to high-density lipoprotein cholesterol (TG/HDL-c) ratio, triglyceride glucose index (TyG) and total cholesterol (TC)/HDL-c to predict the risk of later gestational diabetes mellitus (GDM) and large for gestational age (LGA) newborn in Chinese women.
methodsWe included 352 women with a singleton pregnancy, who were followed up prospectively from the first prenatal visit until delivery. Fasting glucose and plasma lipid profiles including TG, TC, HDL-c, and low-density lipoprotein cholesterol (LDL-c) were measured in the first trimester. A binary logistic regression analysis was performed to determine the odds ratios (ORs) and 95% confidence intervals (CIs) of GDM and LGA according to tertiles of those indices, respectively. Receiver-operating characteristic curve (ROC) and areas under the curve (AUC) were employed to evaluate the ability of those indices to predict the risk of GDM and LGA infants, and differences in the AUC values between them were compared.
resultsWomen with the top tertile of TG/HDL-c or TyG other than TC/HDL-c had a significantly higher risk of GDM (OR
conclusionMaternal first-trimester TG/HDL-c and TyG are both good indicators in predicting the risk of later GDM and LGA newborn, and it may be useful to evaluate them in early pregnancy.
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