ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2020
Association Between Atherosclerosis and Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes Mellitus.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Diabetic retinopathy: why some eyes suffer more - a focus on retina-specific risk factors and metabolic memory.Journal of translational medicine · 2026Review
- Association between albuminuria and prevalent diabetic retinopathy in type 2 diabetes: a cross-sectional study with exploratory analysis by carotid plaque status.Frontiers in endocrinology · 2026Article
- Diagnostic and Prognostic Role of Circulating microRNAs in Patients with Coronary Artery Disease-Impact on Left Ventricle and Arterial Function.Current issues in molecular biology · 2024Article
- Two ferroptosis-specific expressed genes NOX4 and PARP14 are considered as potential biomarkers for the diagnosis and treatment of diabetic retinopathy and atherosclerosis.Diabetology & metabolic syndrome · 2024Article
- Sex-specific association between carotid atherosclerosis and fundus arteriosclerosis in a Chinese population: a retrospective cross-sectional study.European journal of medical research · 2023Article
- TCU-Net: Transformer Embedded in Convolutional U-Shaped Network for Retinal Vessel Segmentation.Sensors (Basel, Switzerland) · 2023Article
- Predictive Value of the Advanced Lipoprotein Profile and Glycated Proteins on Diabetic Retinopathy.Nutrients · 2022Article
- Diabetic retinopathy predicts cardiovascular disease independently of subclinical atherosclerosis in individuals with type 2 diabetes: A prospective cohort study.Frontiers in cardiovascular medicine · 2022Article
- Cardio-Ankle Vascular Index in the Persons with Pre-Diabetes and Diabetes Mellitus in the Population Sample of the Russian Federation.Diagnostics (Basel, Switzerland) · 2021Article
- Type 2 Diabetes and Myocardial Infarction: Recent Clinical Evidence and Perspective.Frontiers in cardiovascular medicine · 2021Review
- Cross-Sectional Analysis of the Involvement of Interleukin-17A in Diabetic Retinopathy in Elderly Individuals with Type 2 Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo explore the association between the atherosclerosis and diabetic retinopathy (DR) in Chinese patients with type 2 diabetes mellitus (T2DM).
methodsThis hospital-based cross-sectional study included 949 patients (700 males and 249 females) with T2DM. The atherosclerotic parameters were assessed using the cardio-ankle vascular index (CAVI), ankle-brachial index (ABI), and carotid plaque. DR was assessed and graded using digital retinal photography and fundus fluorescein angiography as either nonproliferative DR (NPDR) or proliferative DR (PDR). Multiple logistic regression analysis was performed to identify the associations between the atherosclerotic parameters and DR status.
resultsThe prevalence of DR was 23.6% in total patients, including 167 (17.6%) patients with NPDR and 57 (6.0%) patients with PDR. Patients with NPDR and PDR were more likely to have higher prevalence of increased CAVI, increased ABI, and carotid plaque than those without DR. In multivariable adjusted logistic regression analysis, patients with NPDR showed an odds ratio (OR) of 2.59 [95% confidence interval (CI), 1.61-4.19] for increased CAVI, 1.99 (0.62-6.34) for increased ABI, and 1.75 (1.13-2.71) for carotid plaque. Patients with PDR showed an OR of 7.83 (3.52-17.41) for increased CAVI, 10.65 (3.33-34.04) for increased ABI, and 11.40 (2.67-48.63) for carotid plaque.
conclusionBoth NPDR and PDR were independently associated with increased CAVI and presence of carotid plaque in Chinese patients with T2DM.
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