Evidence map›Paper›PMID 32606675›Full record

ReviewInternational journal of nanomedicine2020

Aptamer Hybrid Nanocomplexes as Targeting Components for Antibiotic/Gene Delivery Systems and Diagnostics: A Review.

Navid Rabiee, Sepideh Ahmadi, Zeynab Arab, Mojtaba Bagherzadeh, Moein Safarkhani, Behzad Nasseri, Mohammad Rabiee, Mohammadreza Tahriri, Thomas J Webster, Lobat Tayebi

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Aptasensors versus immunosensors-Which will prevail?Engineering in life sciences · 2022
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Navid RabieeDepartment of Chemistry, Sharif University of Technology, Tehran, Iran.ORCID 0000-0002-6945-8541
Sepideh AhmadiStudent Research Committee, Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Zeynab ArabDepartment of Chemistry, Sharif University of Technology, Tehran, Iran.
Mojtaba BagherzadehDepartment of Chemistry, Sharif University of Technology, Tehran, Iran.
Moein SafarkhaniDepartment of Chemistry, Sharif University of Technology, Tehran, Iran.
Behzad NasseriChemical Engineering Department and Bioengineering Division, Hacettepe University, Beytepe, Ankara 06800, Turkey.
Mohammad RabieeBiomaterial Group, Department of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran.
Mohammadreza TahririMarquette University School of Dentistry, Milwaukee, WI 53233, USA.ORCID 0000-0002-8806-3924
Thomas J WebsterDepartment of Chemical Engineering, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0002-2028-5969
Lobat TayebiMarquette University School of Dentistry, Milwaukee, WI 53233, USA.ORCID 0000-0003-1947-5658
Sharif University of Technology · IRMarquette University · USAmirkabir University of Technology · IRAtilim University · TRNortheastern University · USShahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the passage of time and more advanced societies, there is a greater emergence and incidence of disease and necessity for improved treatments. In this respect, nowadays, aptamers, with their better efficiency at diagnosing and treating diseases than antibodies, are at the center of attention. Here, in this review, we first investigate aptamer function in various fields (such as the detection and remedy of pathogens, modification of nanoparticles, antibiotic delivery and gene delivery). Then, we present aptamer-conjugated nanocomplexes as the main and efficient factor in gene delivery. Finally, we focus on the targeted co-delivery of genes and drugs by nanocomplexes, as a new exciting approach for cancer treatment in the decades ahead to meet our growing societal needs.

Indexed as

Gene Transfer TechniquesAnti-Bacterial AgentsAptamers, NucleotideDrug Delivery SystemsHumansNanoparticlesPolyethyleneimineAnti-Bacterial AgentsAptamers, NucleotidePolyethyleneimineantibioticaptamergene delivery systemshybrid nanocomplexespolyethyleneiminetargeting

Identifiers

PMID32606675
PMCPMC7314593
OpenAlexW3035583165

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.