Evidence map›Paper›PMID 32606669›Full record

ArticleInternational journal of nanomedicine2020

Effect of

Jiashu Wu, Meiling Zhang, Jinjun Cheng, Yue Zhang, Juan Luo, Yuhan Liu, Hui Kong, Huihua Qu, Yan Zhao

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Carbon Dots Derived fromInternational journal of nanomedicine · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Molecules (Basel, Switzerland) · 2023
    Article
  16. Review
  17. Carbon Dots for the Treatment of Inflammatory Diseases: An Appraisal ofOxidative medicine and cellular longevity · 2023
    Review
  18. Review
  19. Network Pharmacology-Based Analysis onJournal of oncology · 2022
    Article
  20. Protective Effects of Carbon Dots Derived fromInternational journal of nanomedicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jiashu WuSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.
Meiling ZhangSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.
Jinjun ChengSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.
Yue ZhangSchool of Science Life, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.
Juan LuoSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.
Yuhan LiuSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.
Hui KongSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.ORCID 0000-0002-1382-7985
Huihua QuCenter of Scientific Experiment, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.
Yan ZhaoSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionA correlation is established between the efficacy of Chinese herbal medicine and its charcoal drugs.

aimThe aim of this study was to explore the effects of LJFC-derived carbon dots (LJFC-CDs) on lipopolysaccharide (LPS)-induced fever and hypothermia rat models.

methodsLJFC-CDs were characterized using transmission electron microscopy, high-resolution transmission electron microscopy, Fourier-transform infrared, ultraviolet, fluorescence, X-ray photoelectron spectroscopy, X-ray diffraction and high-performance liquid chromatography. The anti-inflammatory effects of LJFC-CDs were evaluated and confirmed using rat models of LPS-induced fever or hypothermia.

resultsThe LJFC-CDs ranged from 1.0 to 10.0 nm in diameter, with a yield of 0.5%. LJFC-CDs alleviated LPS-induced inflammation, as demonstrated by the expression of tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 and the recovery of normal body temperature.

conclusionLJFC-CDs may have an anti-inflammatory effect and a potential to alleviate fever and hypothermia caused by inflammation.

Indexed as

AnimalsBody TemperatureCarbonChromatography, High Pressure LiquidCyclic AMPCytokinesDinoprostoneDisease Models, AnimalDrugs, Chinese HerbalFeverHypothermiaInflammation MediatorsLipopolysaccharidesLoniceraMaleMiceCarbonCyclic AMPCytokinesDinoprostoneDrugs, Chinese HerbalInflammation MediatorsLipopolysaccharideslonicerae flosPlant Extractsanti-inflammatorycarbon dotslipopolysaccharideLonicerae japonicae Flos

Identifiers

PMID32606669
PMCPMC7297362

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.