Evidence map›Paper›PMID 32606663›Full record

ArticleInternational journal of nanomedicine2020

Size-Controlled Preparation and Behavior Study of Phospholipid-Calcium Carbonate Hybrid Nanoparticles.

Cheng Wang, Shaoqing Chen, Lu Bao, Xuerong Liu, Fuqiang Hu, Hong Yuan

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cheng WangCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, People's Republic of China.
Shaoqing ChenCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, People's Republic of China.
Lu BaoCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, People's Republic of China.
Xuerong LiuCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, People's Republic of China.
Fuqiang HuCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, People's Republic of China.
Hong YuanCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCalcium carbonate (CC) nanoparticles have broad biomedical utilizations, owing to their multiple intrinsic merits. However, bare CC nanoparticles do not allow for the development of multifunctional devices suitable for advanced drug delivery in cancer therapy.

methodsPhospholipid-modified phospholipid-CC hybrid nanoparticles were prepared in our study using a combination of vapor-diffusion and solvent-diffusion methods to offer optimized pharmaceutical capabilities.

resultsConsidering that particle size is a critical parameter that plays an important role in both in vitro and in vivo behaviors of nanoparticles, we here for the first time a present detailed protocol for the size-controlled preparation of hybrid nanoparticles, as well as analysis of the in vitro/in vivo behaviors of differently sized hybrid nanoparticles.

conclusionOur results might significantly advance the application of this promising material in more varied fields.

Indexed as

Particle SizeAnimalsCalcium CarbonateCell LineCell Membrane PermeabilityDrug Delivery SystemsEndocytosisFemaleHumansLysosomesMice, Inbred BALB CNanoparticlesPhospholipidsRabbitsSpheroids, CellularStatic ElectricityCalcium CarbonatePhospholipidscalcium carbonatehybrid nanoparticlesphospholipid

Identifiers

PMID32606663
PMCPMC7293410

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.