ArticleIn vivo (Athens, Greece)
Taller-than-wide Thyroid Nodules With Microcalcifications Are at High Risk of Malignancy.
Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 15 citations in OpenAlex.
- The Importance of the Taller-than-Wide Feature and the Dimensions of Focal Thyroid Lesions in Assessing the Risk of Malignancy.Diagnostics (Basel, Switzerland) · 2026Article
- Nomogram integrating BRAF V600E, serum biomarkers, and ultrasound features for malignancy risk stratification in C-TIRADS category 3 and 4 thyroid nodules.Frontiers in medicine · 2026Article
- Clinicopathological Significance of Ultrasound Risk Features and the Taller-Than-Wide Sign for Tumor Advancement in Differentiated Thyroid Cancer: A Single-Center Analysis.Cancer management and research · 2026Article
- Article
- The Role of Ultrasound as a Predictor of Malignancy in Indeterminate Thyroid Nodules-A Multicenter Study.Medicina (Kaunas, Lithuania) · 2025Article
- Correlation between EpCAM expression and cervical lymph node metastasis in papillary thyroid carcinoma: a study integrating ultrasonographic features.BMC cancer · 2025Article
- Thyroid Nodule Sphericity Metrics Discriminate Benign and Malignant Follicular and Oncocytic Neoplasms.Thyroid : official journal of the American Thyroid Association · 2025Article
- Prediction of malignancy risk in Bethesda III nodules: development and validation of multiple machine learning models.Frontiers in endocrinology · 2025Article
- Imprinted gene detection effectively improves the diagnostic accuracy for papillary thyroid carcinoma.BMC cancer · 2024Article
- Histopathological Analysis of Thyroid Nodules with Taller-Than-Wide Shape in Adults.International journal of general medicine · 2024Article
- Clinical value of dual-energy CT for predicting occult metastasis in central neck lymph nodes of papillary thyroid carcinoma.European radiology · 2024Article
- The value of color Doppler ultrasound in the diagnosis of thyroid nodules: a systematic review and meta-analysis.Gland surgery · 2021Article
- Ultrasound Echogenicity of Papillary Thyroid Cancer Is Affected by Tumor Growth Patterns and Tumor Fibrosis.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimPrevious studies have shown that there may be a diversity in the ultrasonographic (US) features discriminating a malignant from a benign thyroid nodule. We determined the reliability of the specific nodule shape in combination with other US features in predicting thyroid carcinomas. PATIENTS AND
methodsThis was a retrospective single-center study investigating the association of the morphological characteristics of nodular goiters from preoperative US and color Doppler images with malignancy based on pathology.
resultsWe evaluated 254 thyroid nodules (malignant, n=131) from 205 patients. Multivariable logistic regression analysis showed that taller-than-wide shape [odds ratio (OR)=25.3, 95% confidence interval (CI)=5.4-118.9; p<0.001], microcalcifications (OR=4.9, 95% CI=2.5-9.5; p<0.001), hypoechogenicity (OR=4.5; 95% CI=2-10.3; p<0.001) and size (OR=0.93; 95% CI=0.89-0.98; p=0.002) were independently associated with thyroid nodule malignancy. Additionally, we found a strong negative correlation between size and taller-than-wide shape of a thyroid nodule (r=-0.41, p<0.001).
conclusionAmong the important indicators of thyroid malignancy, taller-than-wide nodules with microcalcifications are most likely to be malignant.
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